Near-infrared fluorescence imaging-guided surgery improves recurrence-free survival rate in novel orthotopic animal model of head and neck squamous cell carcinoma, Head & Neck, vol.21, issue.S1, pp.246-255, 2016. ,
DOI : 10.1021/bc100070g
Modulation of Cancer Traits by Tumor Suppressor microRNAs, International Journal of Molecular Sciences, vol.128, issue.1, pp.1822-1864, 2013. ,
DOI : 10.1002/ijc.25376
Integrin structures and conformational signaling, Current Opinion in Cell Biology, vol.18, issue.5, pp.579-86, 2006. ,
DOI : 10.1016/j.ceb.2006.08.005
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618925/pdf
Template Assembled Cyclopeptides as Multimeric System for Integrin Targeting and Endocytosis, Journal of the American Chemical Society, vol.126, issue.18, pp.5730-5739, 2004. ,
DOI : 10.1021/ja049926n
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature, Arthritis Research, vol.3, issue.6, pp.357-61, 2001. ,
DOI : 10.1186/ar327
Integrins in angiogenesis and lymphangiogenesis, Nature Reviews Cancer, vol.99, issue.8, pp.604-621, 2008. ,
DOI : 10.1172/JCI200422087
RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis, Molecular Pharmaceutics, vol.9, issue.11, pp.2961-73, 2012. ,
DOI : 10.1021/mp3002733
Chemoselectively Addressable Template:?? A Valuable Tool for the Engineering of Molecular Conjugates, The Journal of Organic Chemistry, vol.71, issue.6, pp.2402-2412, 2006. ,
DOI : 10.1021/jo0525480
The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy, The British Journal of Radiology, vol.11, issue.1041, p.20140134, 1041. ,
DOI : 10.1016/j.nano.2014.05.005.
URL : https://hal.archives-ouvertes.fr/hal-01286747
Les nanoparticules pour le traitement des eaux, 2010. ,
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review, Journal of Controlled Release, vol.65, issue.1-2, pp.271-84, 2000. ,
DOI : 10.1016/S0168-3659(99)00248-5
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs, Cancer Res. déc, vol.4612, issue.1, pp.6387-92, 1986. ,
Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment, Proceedings of the National Academy of Sciences, vol.276, issue.6, pp.4607-4619, 1998. ,
DOI : 10.1038/scientificamerican0697-111
Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness, The American Journal of Pathology, vol.156, issue.4, pp.1363-80, 2000. ,
DOI : 10.1016/S0002-9440(10)65006-7
URL : http://europepmc.org/articles/pmc1876882?pdf=render
Exploiting the enhanced permeability and retention effect for tumor targeting, Drug Discovery Today, vol.11, issue.17-18, pp.17-18812, 2006. ,
DOI : 10.1016/j.drudis.2006.07.005
Future directions of liposome- and immunoliposome-based cancer therapeutics, Seminars in Oncology, vol.31, issue.6, pp.196-205, 2004. ,
DOI : 10.1053/j.seminoncol.2004.08.009
Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models, Cancer Research, vol.66, issue.13, pp.6732-6772, 2006. ,
DOI : 10.1158/0008-5472.CAN-05-4199
Biomaterial-based technologies for brain anticancer therapeutics and imaging, Biochim Biophys Acta. août, vol.1806, issue.1, pp.96-107, 2010. ,
DOI : 10.1016/j.bbcan.2010.04.001
Pharmacokinetic characteristics and anticancer effects of 5-Fluorouracil loaded nanoparticles, BMC Cancer, vol.11, issue.Suppl 2, p.103, 2008. ,
DOI : 10.1016/S0928-0987(00)00166-4
Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA, British Journal of Pharmacology, vol.49, issue.2, pp.179-94, 2009. ,
DOI : 10.1016/0304-4157(94)90001-9
Multifunctional nanocomplexes for gene transfer and gene therapy, Cell Biology and Toxicology, vol.100, issue.1, pp.69-81, 2010. ,
DOI : 10.1161/01.CIR.102.2.231
Lipid-based nanotherapeutics for siRNA delivery, Journal of Internal Medicine, vol.128, issue.1, pp.9-21, 2010. ,
DOI : 10.1038/sj.jid.5701060
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2796.2009.02189.x/pdf
A novel antiangiogenesis therapy using an integrin antagonist or anti???Flk-1 antibody coated 90Y-labeled nanoparticles, International Journal of Radiation Oncology*Biology*Physics, vol.58, issue.4, pp.1215-1242, 2004. ,
DOI : 10.1016/j.ijrobp.2003.10.057
Gold nanoparticles enhance the radiation therapy of a murine squamous cell carcinoma, Physics in Medicine and Biology, vol.55, issue.11, pp.3045-59, 2010. ,
DOI : 10.1088/0031-9155/55/11/004
Medical application of functionalized magnetic nanoparticles, Journal of Bioscience and Bioengineering, vol.100, issue.1, pp.1-11, 2005. ,
DOI : 10.1263/jbb.100.1
Magnetic nanoparticles for interstitial thermotherapy ??? feasibility, tolerance and achieved temperatures, International Journal of Hyperthermia, vol.25, issue.8, pp.673-85, 2006. ,
DOI : 10.1200/JCO.2005.05.520
Spatiotemporal Temperature Distribution and Cancer Cell Death in Response to Extracellular Hyperthermia Induced by Gold Nanorods, ACS Nano, vol.4, issue.5, pp.2892-900, 2010. ,
DOI : 10.1021/nn901884d
Nanoparticles in photodynamic therapy: An emerging paradigm, Advanced Drug Delivery Reviews, vol.60, issue.15, pp.1627-1664, 2008. ,
DOI : 10.1016/j.addr.2008.08.003
Gadolinium(III) Chelates as MRI Contrast Agents:?? Structure, Dynamics, and Applications, Chemical Reviews, vol.99, issue.9, pp.2293-352, 1999. ,
DOI : 10.1021/cr980440x
Targeting and in vivo imaging of non-small-cell lung cancer using nebulized multimodal contrast agents, Proceedings of the National Academy of Sciences, vol.45, issue.1, pp.9247-52, 2014. ,
DOI : 10.1002/1522-2594(200101)45:1<88::AID-MRM1013>3.0.CO;2-N
URL : https://hal.archives-ouvertes.fr/hal-01115890
Biodistribution of ultra small gadolinium-based nanoparticles as theranostic agent: Application to brain tumors, Journal of Biomaterials Applications, vol.28, issue.3, pp.385-94, 2013. ,
DOI : 10.1002/smll.200900563
URL : https://hal.archives-ouvertes.fr/hal-01020860
The use of gold nanoparticles to enhance radiotherapy in mice, Physics in Medicine and Biology, vol.49, issue.18, pp.309-315, 2004. ,
DOI : 10.1088/0031-9155/49/18/N03
Gold nanoparticles: a new X-ray contrast agent, The British Journal of Radiology, vol.79, issue.939, pp.248-53, 2006. ,
DOI : 10.1016/S0002-8703(98)70336-9
Nebulized Gadolinium-Based Nanoparticles: A Theranostic Approach for Lung Tumor Imaging and Radiosensitization, Small, vol.32, issue.2, pp.215-236, 2015. ,
DOI : 10.1016/j.biomaterials.2010.11.063
URL : https://hal.archives-ouvertes.fr/hal-01115895
Toward an Image-Guided Microbeam Radiation Therapy Using Gadolinium-Based Nanoparticles, ACS Nano, vol.5, issue.12, pp.9566-74, 2011. ,
DOI : 10.1021/nn202797h
MR imaging, targeting and characterization of pulmonary fibrosis using intra-tracheal administration of gadolinium-based nanoparticles, Contrast Media & Molecular Imaging, vol.59, issue.5, pp.396-404, 2016. ,
DOI : 10.1002/mrm.21517
URL : https://hal.archives-ouvertes.fr/hal-01405806
Gd-nanoparticles functionalization with specific peptides for ??-amyloid plaques targeting, Journal of Nanobiotechnology, vol.19, issue.1, p.60, 2016. ,
DOI : 10.1016/S0896-6273(00)80974-5
URL : https://hal.archives-ouvertes.fr/hal-01356748
Head and neck cancer-Part 1: Epidemiology, presentation, and preservation, Clinical Otolaryngology, vol.36, issue.1, pp.65-73, 2011. ,
DOI : 10.1111/j.1749-4486.2010.02231.x
How much do smoking and alcohol consumption explain socioeconomic inequalities in head and neck cancer risk?, Journal of Epidemiology & Community Health, vol.65, issue.8, pp.709-723, 2011. ,
DOI : 10.1136/jech.2009.097691
Enhancing epidemiologic research on head and neck cancer: INHANCE ??? The international head and neck cancer epidemiology consortium, Oral Oncology, vol.45, issue.9, pp.743-749, 2009. ,
DOI : 10.1016/j.oraloncology.2009.02.007
Prognostic factors of survival in head and neck cancer patients treated with surgery and postoperative radiation therapy, Acta Oto-Laryngologica, vol.368, issue.6, pp.706-718, 2008. ,
DOI : 10.1016/S0140-6736(06)69121-6
Clinical and histological prognostic factors in locally advanced oral cavity cancers treated with primary surgery, European Annals of Otorhinolaryngology, Head and Neck Diseases, vol.129, issue.6, pp.291-297, 2012. ,
DOI : 10.1016/j.anorl.2012.01.004
Long-Term Results of a Phase III Randomized Trial of Postoperative Radiotherapy With or Without Carboplatin in Patients With High-Risk Head and Neck Cancer, The Laryngoscope, vol.22, issue.3, pp.444-453, 2008. ,
DOI : 10.1016/0360-3016(89)90451-3
Megavoltage X-ray Dose Enhancement with Gold Nanoparticles in Tumor Bearing Mice, Int J Mol Cell Med, vol.2, issue.3, pp.118-141, 2013. ,
Two new human tumor cell lines derived from squamous cell carcinomas of the tongue: Establishment, characterization and response to cytotoxic treatment, European Journal of Cancer and Clinical Oncology, vol.24, issue.9, pp.1445-55, 1988. ,
DOI : 10.1016/0277-5379(88)90335-5
The Principles of Humane Experimental Technique [Internet], Johns Hopkins Bloomberg School of Public Health ,
Characterization of a new rat model of head and neck squamous cell carcinoma, Vivo Athens Greece. août, vol.22, issue.4, pp.403-411, 2008. ,
Mouse models for human head and neck squamous cell carcinomas, Head & Neck, vol.2, issue.10, pp.945-54, 2006. ,
DOI : 10.1001/archotol.1997.01900010022003
An orthotopic nude mouse model of oral tongue squamous cell carcinoma, Clin Cancer Res Off J Am Assoc Cancer Res. janv, vol.8, issue.1, pp.293-301, 2002. ,
Bioluminescent assay of bacterial intracellular AMP, ADP, and ATP with the use of a coimmobilized three-enzyme reagent (adenylate kinase, pyruvate kinase, and firefly luciferase), Anal Biochem. 1 août, vol.220, issue.2, pp.410-414, 1994. ,
A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications, Physiological Reviews, vol.1, issue.2, pp.897-965, 2012. ,
DOI : 10.1021/bc7004297
URL : http://physrev.physiology.org/content/physrev/92/2/897.full.pdf
Functional rafts in cell membranes, Nature, vol.128, issue.6633, pp.569-72, 1997. ,
DOI : 10.1083/jcb.128.6.1043
New Multifunctional Molecular Conjugate Vector for Targeting, Imaging, and Therapy of Tumors, Molecular Therapy, vol.12, issue.6, pp.1168-75, 2005. ,
DOI : 10.1016/j.ymthe.2005.06.095
Integrins, Bioconjugate Chemistry, vol.28, issue.9, pp.2241-2246, 2017. ,
DOI : 10.1021/acs.bioconjchem.7b00362
URL : https://hal.archives-ouvertes.fr/hal-01649349
Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors, Angewandte Chemie International Edition, vol.37, issue.20, p.2754, 1998. ,
DOI : 10.1002/(SICI)1521-3773(19981102)37:20<2754::AID-ANIE2754>3.0.CO;2-3
Multivalency in Ligand Design In Fragment-based Approaches in Drug Discovery Selective tumor cell targeting using low-affinity, multivalent interactions Multivalency as a Chemical Organization and Action Principle Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands Recent Advances in Engineering Polyvalent Biological Interactions Influencing receptor-ligand binding mechanisms with multivalent ligand architecture, Bioconjugate Chemistry Communication DOI: 10.1021/acs.bioconjchem.7b00362 Bioconjugate Chem, pp.2241-2245, 2002. ,
Designing super selectivity in multivalent nano-particle binding Ligandclustered " patchy " nanoparticles for modulated cellular uptake and in vivo tumor targeting Surface functionalization of nanomaterials with dendritic groups: toward enhanced binding to biological targets Thiol-alkyne chemistry for the preparation of micelles with glycopolymer corona: dendritic surfaces versus linear glycopolymer in their ability to bind to lectins, G. (2012) Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection. Nat, pp.1722-1727, 2009. ,
A reevaluation of integrins as regulators of angiogenesis Noninvasive and quantitative assessment of in vivo angiogenesis using RGD-based fluorescence imaging of subcutaneous sponges RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrintargeted drug delivery Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculatureCu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression In vivo optical imaging of integrin ?V-?3 in mice using multivalent or monovalent cRGD targeting vectors Biocompatible well-defined chromophore? polymer conjugates for photodynamic therapy and two-photon imaging Template assembled cyclopeptides as multimeric system for integrin targeting and endocytosis RAFT Nano-constructs: surfing to biological applications Coliposomes comprising a lipidated multivalent RGD-peptide and a cationic gemini cholesterol induce selective gene transfection in ?v?3 and ?v?5 integrin receptor-rich cancer cells Multivalent RGD synthetic peptides as potent alphaVbeta3 integrin ligands Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide Highly efficient cell adhesion on beads functionalized with clustered peptide ligands Development of a selective cell capture and release assay: impact of clustered RGD ligands Living free-radical polymerization by reversible addition?fragmentation chain transfer: The RAFT process Experimental requirements for an efficient control of free-radical polymerizations via the reversible addition-fragmentation chain transfer (RAFT) process Synthesis of N-acryloxysuccinimide copolymers by RAFT polymerization, as reactive building blocks with full control of composition and molecular weights Method for controlled free-radical polymerization, Polym. Sci., Polym. Symp. 51, 135. (10)-acryloylmorpholine) oligomers carrying a ?cyclodextrin residue at one terminus. J. Polym. Sci., Part A: Polym, pp.918-514, 1098. ,
Application of click???click chemistry to the synthesis of new multivalent RGD conjugates, Organic & Biomolecular Chemistry, vol.42, issue.22, pp.1607-1627, 2010. ,
DOI : 10.1039/c0ob00070a
URL : https://hal.archives-ouvertes.fr/inserm-00559554