.. Effet-des-traumatismes-sur-la-pigmentation-de-l-'épiderme, Erreur ! Signet non défini. 2.2.1. Analyse macroscopique de la pigmentation des queues de souris soumise à des frictions répétées, .Erreur ! Signet non défini

A. , H. Butz, S. Stappert, J. Weissig, H. Kemler et al., Assembly of the cadherin-catenin complex in vitro with recombinant proteins, J Cell Sci, vol.107, pp.3655-63, 1994.

A. , H. Schwartz, H. Kemler, and R. , Cadherin-catenin complex: protein interactions and their implications for cadherin function, J Cell Biochem, vol.61, pp.514-537, 1996.

A. Tahir, M. Pramod, K. Ansari, S. H. Ali, and J. , Current remedies for vitiligo, Autoimmunity Reviews, vol.9, issue.7, pp.516-536, 2010.
DOI : 10.1016/j.autrev.2010.02.013

A. , A. Felsten, L. M. Daly, M. &. Petronic-rosic, and V. , Vitiligo: a comprehensive overview Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up, J Am Acad Dermatol, vol.65, pp.473-91, 2011.

O. W. Blaschuk, R. Sullivan, S. David, and Y. Pouliot, Identification of a cadherin cell adhesion recognition sequence, Developmental Biology, vol.139, issue.1, pp.227-236, 1990.
DOI : 10.1016/0012-1606(90)90290-Y

N. Boulais and L. Misery, Merkel cells, Journal of the American Academy of Dermatology, vol.57, issue.1, pp.147-65, 2007.
DOI : 10.1016/j.jaad.2007.02.009

URL : https://hal.archives-ouvertes.fr/hal-01068392

B. , O. Kutsch, S. Hierholzer, A. Delmas, V. Kemler et al., Ecadherin is a survival factor for the lactating mouse mammary gland, Mech Dev, vol.115, pp.53-62, 2002.

B. , S. M. Rimm, D. L. Tonks, and N. K. , Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo, J Cell Biol, vol.130, pp.977-86, 1995.

E. Breen, A. Clarke, G. Steele, J. Mercurio, and A. M. , -Dependent Cell-Cell Adhesion, Cell Adhesion and Communication, vol.77, issue.6, pp.239-50, 1993.
DOI : 10.1016/0092-8674(91)90143-M

URL : https://hal.archives-ouvertes.fr/tel-00474659

B. , M. A. Nitoiu, D. Kelsell, and D. P. , Cell-cell connectivity: desmosomes and disease, J Pathol, vol.226, pp.158-71, 2012.

B. , E. Burada, F. Stoicescu, I. Stanoiu, B. Georgescu et al., Darier disease and Hailey-Hailey disease, Rom J Morphol Embryol, vol.48, pp.423-429, 2007.

C. , M. Pain, C. Gauthier, Y. Taieb, and A. , The melanocytorrhagic hypothesis of vitiligo tested on pigmented, stressed, reconstructed epidermis, Pigment Cell Res, vol.20, pp.385-93, 2007.

C. , H. L. Chou, H. C. Duran, M. Gruenewald, J. Waterfield et al., Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells, J Biol Chem, vol.285, pp.4307-4325, 2009.

C. , X. Koch, and P. J. , In vivo function of desmosomes, J Dermatol, vol.31, pp.171-87, 2004.

C. , S. Berlin, I. Delmas, V. Larue, and L. , Classical and Nonclassical Melanocytes in Vertebrates, Melanins and Melanosomes, 2011.

C. , P. Kapprell, H. P. Franke, W. W. Tamkun, J. Hynes et al., Plakoglobin: a protein common to different kinds of intercellular adhering junctions, Cell, vol.46, pp.1063-73, 1986.

D. , M. A. Ireton, R. C. Reynolds, and A. B. , A core function for p120-catenin in cadherin turnover, J Cell Biol, vol.163, pp.525-559, 2003.

D. , V. Martinozzi, S. Bourgeois, Y. Holzenberger, M. &. Larue et al., Cre-mediated recombination in the skin melanocyte lineage, Genesis, vol.36, pp.73-80, 2003.

D. , F. Pokutta, S. Yamada, S. Nelson, W. J. Weis et al., Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly, Cell, vol.123, pp.903-918, 2005.

F. , M. Fujita, K. Hiiragi, T. Fujimoto, K. Tsukita et al., Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin, J Cell Biol, vol.141, pp.1539-50, 1998.

F. , M. Hirase, T. Itoh, M. Nagafuchi, A. Yonemura et al., Occludin: a novel integral membrane protein localizing at tight junctions, J Cell Biol, vol.123, pp.1777-88, 1993.

G. , L. Schneider-maunoury, S. Voiculescu, O. Charnay, P. Barrandon et al., Pattern of expression of the transcription factor Krox-20 in mouse hair follicle, Mech Dev, vol.96, pp.215-223, 2000.

G. , Y. Cario-andre, M. &. Taieb, and A. , A critical appraisal of vitiligo etiologic theories. Is melanocyte loss a melanocytorrhagy?, Pigment Cell Res, vol.16, pp.322-354, 2003.

G. , Y. Cario-andre, M. Lepreux, S. Pain, C. Taieb et al., Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo, Br J Dermatol, vol.148, pp.95-101, 2003.

H. , M. Yaar, M. &. Gilchrest, and B. A. , Endothelin-1 of keratinocyte origin is a mediator of melanocyte dendricity, J Invest Dermatol, vol.105, pp.744-752, 1995.

H. , L. Heidenheim, M. Gervil, M. Hjalgrim, H. Hoier-madsen et al., High frequency of thyroid dysfunction in patients with vitiligo, Acta Derm Venereol, vol.74, pp.120-123, 1994.

H. , M. M. Lee, E. S. Koo, and J. Y. , Stress as an influencing factor in psoriasis, Skin Therapy Lett, vol.16, pp.1-4, 2011.

H. , C. L. Eide, M. J. Johnson, C. C. Krajenta, R. Jacobsen et al., Incidence of nonmelanoma skin cancer in a cohort of patients with vitiligo, J Am Acad Dermatol, vol.60, pp.929-962, 2009.

H. , M. Y. Wheelock, M. J. Johnson, K. R. Herlyn, and M. , Shifts in cadherin profiles between human normal melanocytes and melanomas, J Investig Dermatol Symp Proc, vol.1, pp.188-94, 1996.

H. , O. Kemler, R. Langosch, and D. , Mutations affecting transmembrane segment interactions impair adhesiveness of E-cadherin, J Cell Sci, vol.112, pp.4415-4438, 1999.

H. , G. Kyne, S. Ito, S. Wakamatsu, K. Todd et al., Eumelanin and phaeomelanin contents of human epidermis and cultured melanocytes, Pigment Cell Res, vol.8, pp.202-210, 1995.

H. , G. K. Pitts, and J. D. , Non-selective junctional communication between some different mammalian cell types in primary culture, J Cell Sci, vol.49, pp.163-75, 1981.

J. , Y. P. Wang, H. D-'eustachio, P. Musacchio, J. M. Schlessinger et al., Cloning and characterization of R-PTP-kappa, a new member of the receptor protein tyrosine phosphatase family with a proteolytically cleaved cellular adhesion molecule-like extracellular region, Mol Cell Biol, vol.13, pp.2942-51, 1993.

K. , A. J. Dogra, and S. , Narrow-band UVB for the treatment of generalized vitiligo in children, Clin Exp Dermatol, vol.30, pp.332-338, 2005.

K. , R. Ozawa, and M. , Uvomorulin-catenin complex: cytoplasmic anchorage of a Ca2+-dependent cell adhesion molecule, Bioessays, vol.11, pp.88-91, 1989.

K. , N. Kathuria, S. D. Ramesh, and V. , Tissue grafts in vitiligo surgery -past, present, and future, Indian J Dermatol, vol.54, pp.150-158, 2009.

K. , S. Bernd, A. Loitsch, S. Muller, J. Guschel et al., Cyclic stretch up-regulates proliferation and heat shock protein 90 expression in human melanocytes, Pigment Cell Res, vol.12, pp.246-51, 1999.

K. , J. Denman, C. J. Hernandez, C. Wainwright, D. A. Strickland et al., Reduced skin homing by functional Treg in vitiligo, Pigment Cell Melanoma Res, vol.23, pp.276-86, 2010.

K. , J. Miosge, and N. , Basement membrane components are key players in specialized extracellular matrices, Cell Mol Life Sci, vol.67, pp.2879-95, 2010.

K. , R. Parsad, D. Kanwar, and A. J. , Role of apoptosis and melanocytorrhagy: a comparative study of melanocyte adhesion in stable and unstable vitiligo, Br J Dermatol, vol.164, pp.187-91, 2011.

L. , P. W. Zijderveld, A. Linders, K. Rudnicki, M. A. Jaenisch et al., Simplified mammalian DNA isolation procedure, Nucleic Acids Res, vol.19, p.4293, 1991.

L. , L. Antos, C. Butz, S. Huber, O. Delmas et al., A role for cadherins in tissue formation, Development, vol.122, pp.3185-94, 1996.

L. , L. Delmas, and V. , The WNT/Beta-catenin pathway in melanoma, Front Biosci, vol.11, pp.733-775, 2006.

L. , L. Kumasaka, M. &. Goding, and C. R. , Beta-catenin in the melanocyte lineage, Pigment Cell Res, vol.16, pp.312-319, 2003.

L. , L. Ohsugi, M. Hirchenhain, J. Kemler, and R. , E-cadherin null mutant embryos fail to form a trophectoderm epithelium, Proc Natl Acad Sci, vol.91, pp.8263-8270, 1994.

L. , T. S. Beers, W. H. Gilula, and N. B. , Transmission of hormonal stimulation by cell-to-cell communication, Nature, vol.272, pp.501-507, 1978.

L. Poole, I. C. Van-den-wijngaard, R. M. Westerhof, W. Das, and P. K. , Tenascin is overexpressed in vitiligo lesional skin and inhibits melanocyte adhesion, British Journal of Dermatology, vol.137, issue.2, pp.171-179, 1997.
DOI : 10.1046/j.1365-2133.1997.18011894.x

L. , G. Schaider, H. Satyamoorthy, K. Hanakawa, Y. Hashimoto et al., Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development, Oncogene, vol.20, pp.8125-8160, 2001.

L. , Z. Kim, S. H. Higgins, J. M. Brenner, M. B. Sacks et al., IQGAP1 and calmodulin modulate E-cadherin function, J Biol Chem, vol.274, pp.37885-92, 1999.

L. , P. Y. Bondesson, L. Lontz, W. Johansson, and O. , The occurrence of cutaneous nerve endings and neuropeptides in vitiligo vulgaris: a case-control study, Arch Dermatol Res, vol.288, pp.670-675, 1996.

M. , M. A. Jordan, S. A. Budd, P. S. Jackson, and I. J. , Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo, Dev Biol, vol.192, pp.99-107, 1997.

M. , V. Flori, E. Briganti, S. Camera, E. Cario-andre et al., UVA-induced modification of catalase charge properties in the epidermis is correlated with the skin phototype, J Invest Dermatol, vol.126, pp.182-90, 2006.

M. , V. Roccella, M. Roccella, F. Camera, E. Del-porto et al., Increased sensitivity to peroxidative agents as a possible pathogenic factor of melanocyte damage in vitiligo, J Invest Dermatol, vol.109, pp.310-313, 1997.

M. , R. W. Yap, and A. S. , Not so simple: the complexity of phosphotyrosine signaling at cadherin adhesive contacts, J Mol Med (Berl), vol.85, pp.545-54, 2007.

M. , O. G. Delmas, V. Moore, R. Jeanney, C. Thiery et al., IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition, Oncogene, vol.20, pp.4942-50, 2001.

M. , K. Miyachi, and Y. , Tight junctions in the skin, J Dermatol Sci, vol.31, pp.81-90, 2003.

N. , B. Overduin, M. Ikura, M. &. Rini, and J. M. , Structural basis of calciuminduced E-cadherin rigidification and dimerization, Nature, vol.380, pp.360-364, 1996.

N. , K. Kalassy, M. Sahuc, F. Collombel, C. Damour et al., Pigmented human skin equivalent--as a model of the mechanisms of control of cell-cell and cell-matrix interactions, Med Biol Eng Comput, vol.36, pp.813-833, 1998.
URL : https://hal.archives-ouvertes.fr/hal-00313898

N. , G. K. Eisinger, M. &. Bystryn, and J. C. , Antibodies to normal human melanocytes in vitiligo, J Exp Med, vol.158, pp.246-51, 1983.

N. , C. M. Leckband, D. Yap, and A. S. , Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation, Physiol Rev, vol.91, pp.691-731, 2011.

N. , N. Bito, T. Ikeda, T. Tokura, Y. Nishigori et al., Complete remission of metastatic malignant melanoma after surgery in association with development of systemic vitiligo, J Dermatol, vol.37, pp.770-772, 2010.

N. , F. Kools, P. Van-roy, and F. , Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members, J Mol Biol, vol.299, pp.551-72, 2000.

O. , K. Van-geel, N. Naeyaert, and J. M. , Evidence for an autoimmune pathogenesis of vitiligo, Pigment Cell Res, vol.16, pp.90-100, 2003.

O. , J. P. Bose, and S. K. , Vitiligo: where do we stand?, Pigment Cell Res, vol.6, pp.61-72, 1993.

O. , J. P. Macdonald, D. M. Micoud, A. Thivolet, and J. , PUVA-induced repigmentation of vitiligo: a histochemical (split-DOPA) and ultrastructural study, Br J Dermatol, vol.101, pp.1-12, 1979.

O. , M. Baribault, H. Kemler, and R. , The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species, EMBO J, vol.8, pp.1711-1718, 1989.

P. , O. Bozic, D. Koch, A. W. Fauser, C. Brancaccio et al., A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation, EMBO J, vol.18, pp.1738-1785, 1999.

P. , S. Drees, F. Takai, Y. Nelson, W. J. Weis et al., Biochemical and structural definition of the l-afadin-and actin-binding sites of alpha-catenin, J Biol Chem, vol.277, pp.18868-74, 2002.

P. , E. Brandner, J. M. Jensen, and J. M. , The skin: an indispensable barrier, Exp Dermatol, vol.17, pp.1063-72, 2008.

P. , D. M. Cadwallader, G. P. Pitts, and J. D. , E-cadherin expression can alter the specificity of gap junction formation, Cell Biol Int, vol.21, pp.833-876, 1997.

Q. , X. Karpova, T. Sheppard, A. M. Mcnally, J. Lowy et al., E-cadherinmediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases, EMBO J, vol.23, pp.1739-1787, 2004.

R. , G. L. Rayburn, H. Matsunami, H. Knudsen, K. A. Takeichi et al., Developmental defects in mouse embryos lacking N-cadherin, Dev Biol, vol.181, pp.64-78, 1997.

R. , R. K. Basuroy, S. Rao, V. U. Karnaky-jr, K. J. Gupta et al., Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress, Biochem J, vol.368, pp.471-81, 2002.

R. , D. L. Koslov, E. R. Kebriaei, P. Cianci, C. D. Morrow et al., Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex, Proc Natl Acad Sci, vol.92, pp.8813-8820, 1995.

R. , S. Miravet, S. Piedra, J. Garcia-de-herreros, A. Dunach et al., Regulation of E-cadherin/Catenin association by tyrosine phosphorylation, J Biol Chem, vol.274, pp.36734-36774, 1999.

S. , L. Trau, and H. , The Koebner phenomenon, Clin Dermatol, vol.29, pp.231-237, 2011.

S. , K. U. Gibbons, N. C. Zothner, C. Abou-elloof, M. M. Wood et al., Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: more evidence for oxidative stress in vitiligo, Biochem Biophys Res Commun, vol.360, pp.70-75, 2007.

S. , K. U. Moore, J. Wood, J. M. Beazley, W. D. Gaze et al., In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase, J Investig Dermatol Symp Proc, vol.4, pp.91-97, 1999.

S. , K. U. Pittelkow, and M. P. , Defective calcium uptake in keratinocyte cell cultures from vitiliginous skin, Arch Dermatol Res, vol.280, pp.137-146, 1988.

S. , K. U. Wood, J. M. Berger, and J. , Low catalase levels in the epidermis of patients with vitiligo, J Invest Dermatol, vol.97, pp.1081-1086, 1991.

S. , K. U. Pittelkow, M. R. Swanson, and N. N. , Defective calcium transport in vitiliginous melanocytes, Arch Dermatol Res, vol.288, pp.11-14, 1996.

S. , E. E. Lynch, and R. D. , Structure, function, and regulation of cellular tight junctions, Am J Physiol, vol.262, pp.647-61, 1992.

S. , S. Hayakawa, M. Takeuchi, K. Hori, T. Miyazawa et al., Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes, J Cell Biol, vol.128, pp.949-57, 1995.

S. , R. Karayiannakis, A. J. Syrigos, K. N. Poole, S. Van-noorden et al., E-cadherin/catenin complex in benign and malignant melanocytic lesions, J Pathol, vol.186, pp.350-355, 1998.

T. , A. Picardo, and M. , The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force, Pigment Cell Res, vol.20, pp.27-35, 2007.

A. Tang, M. S. Eller, M. Hara, M. Yaar, S. Hirohashi et al., E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro, J Cell Sci, vol.107, pp.983-92, 1994.

T. , C. L. Lechler, T. Pasolli, H. A. Fuchs, and E. , Conditional targeting of Ecadherin in skin: insights into hyperproliferative and degenerative responses, Proc Natl Acad Sci U S A, vol.101, pp.552-559, 2004.

T. , M. Stoykova, A. Huber, O. Chowdhury, K. Bonaldo et al., An alpha-E-catenin gene trap mutation defines its function in preimplantation development, Proc Natl Acad Sci, vol.94, pp.901-907, 1997.

T. , C. Zhao, D. Lin, and X. , Levels of neuropeptide-Y in the plasma and skin tissue fluids of patients with vitiligo, J Dermatol Sci, vol.27, pp.178-82, 2001.

T. , J. A. Helfrich, I. Schmitz, A. Schwarz, H. Gunzel et al., E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions, EMBO J, vol.24, pp.1146-56, 2005.

N. Van-geel, R. Speeckaert, A. Taieb, M. Picardo, M. Bohm et al., Koebner???s phenomenon in vitiligo: European position paper, Pigment Cell & Melanoma Research, vol.20, issue.3, pp.564-73, 2011.
DOI : 10.1111/j.1755-148X.2011.00838.x

V. , V. Bauer, C. Degenstein, L. Wise, B. Fuchs et al., Hyperproliferation and defects in epithelial polarity upon conditional ablation of alphacatenin in skin, Cell, vol.104, pp.605-622, 2001.

W. , M. Assen, Y. J. Thio, H. B. Neumann, and H. A. , Repigmentation of vitiligo during efalizumab, J Am Acad Dermatol, vol.59, pp.57-65, 2008.

W. , L. Limat, A. Saurat, J. H. Meda, P. Salomon et al., Differential expression of connexins during stratification of human keratinocytes, J Invest Dermatol, vol.115, pp.278-85, 2000.

Y. , R. Omidian, M. &. Bagherani, and N. , Vitiligo: a review of the published work, J Dermatol, vol.38, pp.419-450, 2011.

Y. , T. Takeichi, and M. , Cadherin superfamily genes: functions, genomic organization, and neurologic diversity, Genes Dev, vol.14, pp.1169-80, 2000.

Y. , I. Belloir, E. Bourgeois, Y. Kumasaka, M. Delmas et al., Spatiotemporal gene control by the Cre-ERT2 system in melanocytes, Genesis, vol.44, pp.34-43, 2006.

Y. , S. Pokutta, S. Drees, F. Weis, W. I. Nelson et al., Deconstructing the cadherin-catenin-actin complex, Cell, vol.123, pp.889-901, 2005.

Y. , J. J. Norris, D. A. Yrastorza, D. G. Buno, I. J. Leff et al., Disparate antioxidant enzyme activities in cultured human cutaneous fibroblasts, keratinocytes, and melanocytes, J Invest Dermatol, vol.97, pp.405-414, 1991.

Y. , P. Boussadia, O. Halfter, H. Grose, R. Berger et al., E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles, EMBO J, vol.22, pp.5723-5756, 2003.