I. La-polyarthrite-rhumatoïde, .. De, and P. , 19 I-D-2-a Les modèles murins, p.20

G. Algire, F. Legallais, and B. Anderson, Vascular reactions of normal and malignant tissues in vivo

A. Almeida, B. Zaragoza, and A. Freitas, Competition controls the rate of transition between the peripheral pools of CD4+CD25- and CD4+CD25+ T cells, International Immunology, vol.18, issue.11, pp.1607-1620, 2006.
DOI : 10.1093/intimm/dxl093
URL : https://hal.archives-ouvertes.fr/pasteur-00161685

B. Alvarado-sánchez, B. Hernández-castro, D. Portales-pérez, L. Baranda, E. Layseca-espinosa et al., Regulatory T cells in patients with systemic lupus erythematosus, Journal of Autoimmunity, vol.27, issue.2, pp.110-118, 2006.
DOI : 10.1016/j.jaut.2006.06.005

R. Audo, J. Morel, M. Hahne, and B. Combe, Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt, J Biol Chem, vol.280, issue.16, pp.15709-15727, 2005.

H. Bagavant and K. Tung, Failure of CD25+ T Cells from Lupus-Prone Mice to Suppress Lupus Glomerulonephritis and Sialoadenitis, The Journal of Immunology, vol.175, issue.2, pp.944-50, 2005.
DOI : 10.4049/jimmunol.175.2.944

J. Bluestone and A. Abbas, Natural versus adaptive regulatory T cells, Nat Rev Immunol, 2003.

J. Bluestone and Q. Tang, How do CD4+CD25+ regulatory T cells control autoimmunity?, Current Opinion in Immunology, vol.17, issue.6, pp.638-680, 2005.
DOI : 10.1016/j.coi.2005.09.002

J. Bodmer, P. Schneider, and J. Tschopp, The molecular architecture of the TNF superfamily, Trends in Biochemical Sciences, vol.27, issue.1, pp.19-26, 2002.
DOI : 10.1016/S0968-0004(01)01995-8

M. Bonelli, K. Von-dalwigk, A. Savitskaya, J. Smolen, and C. Scheinecker, Foxp3 expression in CD4+ T cells of patients with systemic lupus erythematosus (SLE): A comparative phenotypic analysis, Ann Rheum Dis, 2007.

R. Brownlie, L. Myers, P. Wooley, V. Corrigall, M. Bodman-smith et al., Treatment of murine collagen-induced arthritis by the stress protein BiP via interleukin-4???producing regulatory T cells: A novel function for an ancient protein, Arthritis & Rheumatism, vol.16, issue.3, pp.854-63, 2006.
DOI : 10.1002/art.21654

P. Bruns, Die Heilwirkung des Erysipels auf Geschwulste, Beitr. Chir, vol.3, pp.443-446, 1868.

J. Cañete, S. Martínez, J. Farrés, R. Sanmartí, M. Blay et al., Differential Th1/Th2 cytokine patterns in chronic arthritis: interferon gamma is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies, Annals of the Rheumatic Diseases, vol.59, issue.4, pp.263-271, 2000.
DOI : 10.1136/ard.59.4.263

E. Castigli, S. Scott, F. Dedeoglu, P. Bryce, H. Jabara et al., Impaired IgA class switching in APRIL-deficient mice, Proceedings of the National Academy of Sciences, vol.101, issue.11, pp.3903-3911, 2004.
DOI : 10.1073/pnas.0307348101
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC374342

A. Chiba, S. Kaieda, S. Oki, T. Yamamura, and S. Miyake, The involvement of V??14 natural killer T cells in the pathogenesis of arthritis in murine models, Arthritis & Rheumatism, vol.201, issue.6, pp.1941-1949, 2005.
DOI : 10.1002/art.21056

A. Chiba, S. Oki, K. Miyamoto, H. Hashimoto, T. Yamamura et al., Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of ?-galactosylceramide, Arthritis & Rheumatism, vol.43, issue.1, pp.305-318, 2004.
DOI : 10.1002/art.11489

W. Coley, CONTRIBUTION TO THE KNOWLEDGE OF SARCOMA, Annals of Surgery, vol.14, pp.199-220, 1891.
DOI : 10.1097/00000658-189112000-00015

K. Coppieters, P. Dewint, K. Van-beneden, P. Jacques, S. Seeuws et al., NKT cells: manipulable managers of joint inflammation, Rheumatology, vol.46, issue.4, 2007.
DOI : 10.1093/rheumatology/kel437

J. Crispin, A. Martínez, and J. Alcocer-varela, Quantification of regulatory T cells in patients with systemic lupus erythematosus, Journal of Autoimmunity, vol.21, issue.3, pp.273-279, 2003.
DOI : 10.1016/S0896-8411(03)00121-5

S. Dillon, J. Gross, S. Ansell, and A. Novak, An APRIL to remember: novel TNF ligands as therapeutic targets, Nature Reviews Drug Discovery, vol.114, issue.3, pp.235-281, 2006.
DOI : 10.1074/jbc.M305754200

H. Ditzel, The K/BxN mouse: a model of human inflammatory arthritis, Trends in Molecular Medicine, vol.10, issue.1, pp.40-45
DOI : 10.1016/j.molmed.2003.11.004

R. Dolhain, A. Van-der-heiden, N. Ter-haar, F. Breedveld, and A. Miltenburg, Shift toward T lymphocytes with a T helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis, Arthritis & Rheumatism, vol.37, issue.12, pp.1961-1970, 1996.
DOI : 10.1002/art.1780391204

M. Ehrenstein, J. Evans, A. Singh, S. Moore, G. Warnes et al., Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNF?? Therapy, The Journal of Experimental Medicine, vol.155, issue.3, pp.277-85, 2004.
DOI : 10.1186/ar414

G. Firestein, Evolving concepts of rheumatoid arthritis, Nature, vol.241, issue.6937, pp.356-61, 2003.
DOI : 10.1093/rheumatology/39.10.1060

J. Fontenot, M. Gavin, and A. Rudensky, Foxp3 programs the development and function of CD4+CD25+ regulatory T cells, Nature Immunology, vol.4, issue.4, pp.330-336, 2003.
DOI : 10.1038/ni904

C. Forestier, A. Molano, J. Im, Y. Dutronc, B. Diamond et al., Expansion and Hyperactivity of CD1d-Restricted NKT Cells during the Progression of Systemic Lupus Erythematosus in (New Zealand Black x New Zealand White)F1 Mice, The Journal of Immunology, vol.175, issue.2, pp.763-70, 2005.
DOI : 10.4049/jimmunol.175.2.763

O. Frey, P. Petrow, M. Gajda, K. Siegmund, J. Huehn et al., The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells, Arthritis Research & Therapy, vol.7, issue.2, pp.291-301, 2005.
DOI : 10.1186/ar1484

F. Furukawa and T. Yoshimasu, Animal models of spontaneous and drug-induced cutaneous lupus erythematosus, Autoimmunity Reviews, vol.4, issue.6, pp.345-50, 2005.
DOI : 10.1016/j.autrev.2005.01.006

U. Gaur and B. Aggarwal, Regulation of proliferation, survival and apoptosis by members of the TNF superfamily, Biochemical Pharmacology, vol.66, issue.8, pp.1403-1411, 2003.
DOI : 10.1016/S0006-2952(03)00490-8

D. Godfrey and M. Kronenberg, Going both ways: Immune regulation via CD1d-dependent NKT cells, Journal of Clinical Investigation, vol.114, issue.10, pp.1379-88, 2004.
DOI : 10.1172/JCI200423594
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525753

F. Graham, Biological Activity of Tumor Virus Dna, Adv Cancer Res, vol.25, pp.1-51, 1977.
DOI : 10.1016/S0065-230X(08)60631-4

P. Gray, B. Aggarwal, C. Benton, T. Bringman, W. Henzel et al., Cloning and expression of cDNA for human lymphotoxin

U. Greber, M. Willetts, P. Webster, and A. Helenius, Stepwise dismantling of adenovirus 2 during entry into cells, Cell, vol.75, issue.3, pp.477-86, 1993.
DOI : 10.1016/0092-8674(93)90382-Z

J. Gross, J. Johnston, S. Mudri, R. Enselman, S. Dillon et al., TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease, Nature, vol.404, issue.6781, pp.995-1004, 2000.
DOI : 10.1038/35010115

M. Hahne, T. Kataoka, M. Schröter, K. Hofmann, M. Irmler et al., APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth, The Journal of Experimental Medicine, vol.188, issue.6, pp.1185-90, 1998.
DOI : 10.1146/annurev.med.45.1.491

S. Han, S. Cao, R. Bheekha-escura, and B. Zheng, Germinal center reaction in the joints of mice with collagen-induced arthritis: An animal model of lymphocyte activation and differentiation in arthritic joints, Arthritis & Rheumatism, vol.118, issue.6, pp.1438-1481, 2001.
DOI : 10.1002/1529-0131(200106)44:6<1438::AID-ART239>3.0.CO;2-Q

T. He, S. Zhou, L. Da-costa, J. Yu, K. Kinzler et al., A simplified system for generating recombinant adenoviruses, Proceedings of the National Academy of Sciences, vol.95, issue.5, pp.2509-2523, 1998.
DOI : 10.1073/pnas.95.5.2509
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC19394

H. Ji, D. Gauguier, K. Ohmura, A. Gonzalez, V. Duchatelle et al., Genetic Influences on the End-Stage Effector Phase of Arthritis, The Journal of Experimental Medicine, vol.158, issue.3, pp.321-351, 2001.
DOI : 10.1038/ng0198-56

H. Kim, H. Kim, H. Min, S. Kim, W. Park et al., NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor ??1 production, The Journal of Experimental Medicine, vol.160, issue.1, pp.41-48, 2005.
DOI : 10.1055/s-2004-822315
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212773

L. Klareskog, L. Padyukov, J. Rönnelid, and L. Alfredsson, Genes, environment and immunity in the development of rheumatoid arthritis, Current Opinion in Immunology, vol.18, issue.6, pp.650-655, 2006.
DOI : 10.1016/j.coi.2006.06.004

T. Koyama, H. Tsukamoto, K. Masumoto, D. Himeji, K. Hayashi et al., A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus, Rheumatology, vol.42, issue.8, pp.980-985, 2003.
DOI : 10.1093/rheumatology/keg270

T. Koyama, H. Tsukamoto, Y. Miyagi, D. Himeji, J. Otsuka et al., Raised serum APRIL levels in patients with systemic lupus erythematosus, Annals of the Rheumatic Diseases, vol.64, issue.7, 2005.
DOI : 10.1136/ard.2004.022491
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1755547

L. Cava, A. Van-kaer, L. , and F. , CD4+CD25+ Tregs and NKT cells: regulators regulating regulators, Trends in Immunology, vol.27, issue.7, pp.322-329, 2006.
DOI : 10.1016/j.it.2006.05.003

J. Leipe, A. Skapenko, P. Lipsky, and H. Schulze-koops, Regulatory T cells in rheumatoid arthritis, Arthritis Research & Therapy, vol.7, issue.3, p.93, 2005.
DOI : 10.1186/ar1718

K. Liu and C. Mohan, What do mouse models teach us about human SLE? Clin Immunol, 2006.
DOI : 10.1016/j.clim.2006.01.014

M. Liu, C. Wang, L. Fung, and C. Wu, Decreased CD4+CD25+ T Cells in Peripheral Blood of Patients with Systemic Lupus Erythematosus, Scandinavian Journal of Immunology, vol.167, issue.2, pp.198-202, 2004.
DOI : 10.1002/immu.200390024

R. Liu, L. Cava, A. Bai, X. Jee, Y. Price et al., Cooperation of Invariant NKT Cells and CD4+CD25+ T Regulatory Cells in the Prevention of Autoimmune Myasthenia, The Journal of Immunology, vol.175, issue.12, pp.7898-904, 2005.
DOI : 10.4049/jimmunol.175.12.7898

W. Liu, A. Szalai, L. Zhao, D. Liu, F. Martin et al., Control of spontaneous B lymphocyte autoimmunity with adenovirus-encoded soluble TACI, Arthritis & Rheumatism, vol.151, issue.6, 2004.
DOI : 10.1002/art.20290

R. Locksley, N. Killeen, and M. Lenardo, The TNF and TNF Receptor Superfamilies, Cell, vol.104, issue.4, pp.487-501, 2001.
DOI : 10.1016/S0092-8674(01)00237-9

E. Lyssuk, A. Torgashina, S. Soloviev, E. Nassonov, and S. Bykovskaia, Reduced number and function of CD4+CD25highFoxP3+ regulatory T cells in patients with systemic lupus erythematosus

D. Macewan, TNF ligands and receptors???-???a matter of life and death, British Journal of Pharmacology, vol.322, issue.4
DOI : 10.1038/sj.bjp.0704549

F. Mackay and S. Kalled, TNF ligands and receptors in autoimmunity: an update, Current Opinion in Immunology, vol.14, issue.6, pp.783-90, 2002.
DOI : 10.1016/S0952-7915(02)00407-7

A. Mathian, A. Weinberg, M. Gallegos, J. Banchereau, and S. Koutouzov, IFN-?? Induces Early Lethal Lupus in Preautoimmune (New Zealand Black x New Zealand White)F1 but Not in BALB/c Mice, The Journal of Immunology, vol.174, issue.5, pp.2499-506, 2005.
DOI : 10.4049/jimmunol.174.5.2499

J. Medema, L. Planelles-carazo, G. Hardenberg, and M. Hahne, The uncertain glory of APRIL. Cell Death Differ, pp.1121-1126, 2003.

M. Mieza, T. Itoh, J. Cui, Y. Makino, T. Kawano et al., Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice, J Immunol, vol.156, issue.10, pp.4035-4075, 1996.

P. Miossec, M. Naviliat, A. Dupuy-d-'angeac, J. Sany, and J. Banchereau, Low levels of interleukin-4 and high levels of transforming growth factor beta in rheumatoid synovitis, Arthritis Rheum, 1990.

S. Miyake and T. Yamamura, NKT Cells and Autoimmune Diseases: Unraveling the Complexity, Curr Top Microbiol Immunol, vol.314, pp.251-67, 2007.
DOI : 10.1007/978-3-540-69511-0_10

M. Miyara, Z. Amoura, C. Parizot, C. Badoual, K. Dorgham et al., Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus, The Journal of Immunology, vol.175, issue.12, pp.8392-400, 2005.
DOI : 10.4049/jimmunol.175.12.8392

C. Monk, M. Spachidou, F. Rovis, E. Leung, M. Botto et al., MRL/Mp CD4+,CD25? T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus, Arthritis & Rheumatism, vol.173, issue.4, 2005.
DOI : 10.1002/art.20976

M. Morgan, R. Flierman, L. Van-duivenvoorde, H. Witteveen, W. Van-ewijk et al., Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells, Arthritis & Rheumatism, vol.104, issue.7, pp.2212-2233, 2005.
DOI : 10.1002/art.21195

P. Mudd, B. Teague, and A. Farris, Regulatory T Cells and Systemic Lupus Erythematosus, Scandinavian Journal of Immunology, vol.48, issue.3, pp.211-219, 2006.
DOI : 10.1084/jem.20050338

D. Mulherin, O. Fitzgerald, and B. Bresnihan, Synovial tissue macrophage populations and articular damage in rheumatoid arthritis, Arthritis & Rheumatism, vol.344, issue.1, pp.115-139, 1996.
DOI : 10.1002/art.1780390116

L. Ng, A. Sutherland, R. Newton, F. Qian, T. Cachero et al., B Cell-Activating Factor Belonging to the TNF Family (BAFF)-R Is the Principal BAFF Receptor Facilitating BAFF Costimulation of Circulating T and B Cells, The Journal of Immunology, vol.173, issue.2, pp.807-824, 2004.
DOI : 10.4049/jimmunol.173.2.807

O. Malley, W. Achinstein, B. Shear, and M. , Action of bacterial polysaccharide on tumors. II. Damage of sarcoma 37 by serum of mice treated with Serratia marcescens polysaccharide, and induced tolerance, Journal of the National Cancer Institute, vol.29, 1962.

Y. Ohnishi, A. Tsutsumi, D. Goto, S. Itoh, I. Matsumoto et al., TCR Valpha14+ natural killer T cells function as effector T cells in mice with collagen-induced arthritis, Clinical and Experimental Immunology, vol.171, issue.1, pp.47-53, 2005.
DOI : 10.1002/eji.200323963

D. Pennica, G. Nedwin, J. Hayflick, P. Seeburg, R. Derynck et al., Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin, Nature, vol.249, issue.5996, pp.312724-312733, 1984.
DOI : 10.1038/312724a0
URL : http://hdl.handle.net/11858/00-001M-0000-0019-AF84-E

M. Mon, J. De-jong, E. Eldering, M. Medema, J. Hahne et al., APRIL promotes B-1 cellassociated neoplasm. Cancer Cell, pp.399-408, 2004.

M. Ramanujam, X. Wang, W. Huang, Z. Liu, L. Schiffer et al., Similarities and differences between selective and nonselective BAFF blockade in murine SLE, Journal of Clinical Investigation, vol.116, issue.3, pp.724-758, 2006.
DOI : 10.1172/JCI26385DS1
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1366500

M. Ramanujam, X. Wang, W. Huang, L. Schiffer, C. Grimaldi et al., Mechanism of Action of Transmembrane Activator and Calcium Modulator Ligand Interactor-Ig in Murine Systemic Lupus Erythematosus, The Journal of Immunology, vol.173, issue.5, pp.3524-3558, 2004.
DOI : 10.4049/jimmunol.173.5.3524

D. Rawlings, D. Saffran, S. Tsukada, D. Largaespada, J. Grimaldi et al., Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice, Science, vol.261, issue.5119, pp.358-61, 1993.
DOI : 10.1126/science.8332901

C. Reilly and G. Gilkeson, Use of Genetic Knockouts to Modulate Disease Expression in a Murine Model of Lupus, MRL/lpr Mice, Immunologic Research, vol.25, issue.2, pp.143-53, 2002.
DOI : 10.1385/IR:25:2:143

U. Rogner and P. Avner, Congenic mice: cutting tools for complex immune disorders, Nature Reviews Immunology, vol.3, issue.3, pp.243-52, 2003.
DOI : 10.1038/nri1031

S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda, Immunologic self-tolerance maintained by EPHE Banque de Monographies SVT activated T cells expressing IL-2 receptor alpha-chains (CD25) Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases, J Immunol, vol.155, issue.3, pp.1151-64, 1995.

M. Santiago-raber, C. Laporte, L. Reininger, and S. Izui, Genetic basis of murine lupus, Autoimmunity Reviews, vol.3, issue.1, pp.33-42
DOI : 10.1016/S1568-9972(03)00062-4

K. Scalapino, Q. Tang, J. Bluestone, M. Bonyhadi, and D. Daikh, Suppression of Disease in New Zealand Black/New Zealand White Lupus-Prone Mice by Adoptive Transfer of Ex Vivo Expanded Regulatory T Cells, The Journal of Immunology, vol.177, issue.3, pp.1451-1460, 2006.
DOI : 10.4049/jimmunol.177.3.1451

F. Schagen, M. Ossevoort, R. Toes, and R. Hoeben, Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion, Critical Reviews in Oncology/Hematology, vol.50, issue.1, 2004.
DOI : 10.1016/S1040-8428(03)00172-0

T. Seyler, Y. Park, S. Takemura, R. Bram, P. Kurtin et al., BLyS and APRIL in rheumatoid arthritis, Journal of Clinical Investigation, vol.115, issue.11, pp.3083-92, 2005.
DOI : 10.1172/JCI25265
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257539

M. Shear and F. Turner, Chemical treatment of tumors. V. Isolation of the hemorrhage-producing fraction from Serratia marcescens (Bacillus prodigiosus) culture filtrate, J Natl Cancer Inst, vol.4, pp.81-97, 1943.

A. Simon, E. Seipelt, and J. Sieper, Divergent T-cell cytokine patterns in inflammatory arthritis., Proceedings of the National Academy of Sciences, vol.91, issue.18, pp.8562-8568, 1994.
DOI : 10.1073/pnas.91.18.8562

J. Stein, M. López-fraga, F. Elustondo, C. Carvalho-pinto, D. Rodríguez et al., APRIL modulates B and T cell immunity, Journal of Clinical Investigation, vol.109, issue.12, pp.1587-98, 2002.
DOI : 10.1172/JCI0215034
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151011

W. Stohl, S. Metyas, S. Tan, G. Cheema, B. Oamar et al., Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus, Annals of the Rheumatic Diseases, vol.63, issue.9, pp.1096-103, 2004.
DOI : 10.1136/ard.2003.018663

A. Suryaprasad and T. Prindiville, The biology of TNF blockade, Autoimmunity Reviews, vol.2, issue.6, pp.346-57, 2003.
DOI : 10.1016/S1568-9972(03)00048-X

K. Takeda and G. Dennert, The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms, Journal of Experimental Medicine, vol.177, issue.1, pp.155-64, 1993.
DOI : 10.1084/jem.177.1.155

S. Tan, D. Xu, V. Roschke, J. Perry, D. Arkfeld et al., Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis, Arthritis & Rheumatism, vol.48, issue.4, pp.982-92, 2003.
DOI : 10.1002/art.10860

Q. Tang and J. Bluestone, Regulatory T-cell physiology and application to treat autoimmunity., Immunological Reviews, vol.252, issue.1, pp.217-254, 2006.
DOI : 10.1182/blood-2004-10-3888

A. Theofilopoulos, D. Shawler, R. Eisenberg, and F. Dixon, Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice, Journal of Experimental Medicine, vol.151, issue.2, pp.446-66, 1980.
DOI : 10.1084/jem.151.2.446

X. Valencia, C. Yarboro, G. Illei, and P. Lipsky, Deficient CD4+CD25high T Regulatory Cell Function in Patients with Active Systemic Lupus Erythematosus, The Journal of Immunology, vol.178, issue.4, pp.2579-88, 2007.
DOI : 10.4049/jimmunol.178.4.2579

J. Van-amelsfort, K. Jacobs, J. Bijlsma, F. Lafeber, and L. Taams, CD4+CD25+ regulatory T cells in rheumatoid arthritis: Differences in the presence, phenotype, and function between peripheral blood and synovial fluid, Arthritis & Rheumatism, vol.159, issue.9, pp.2775-85, 2004.
DOI : 10.1002/art.20499

J. Van-roon, J. Bijlsma, and F. Lafeber, Diversity of regulatory T cells to control arthritis, Best Practice & Research Clinical Rheumatology, vol.20, issue.5, pp.897-913, 2006.
DOI : 10.1016/j.berh.2006.06.006

J. Van-roon, J. Bijlsma, and F. Lafeber, Suppression of inflammation and joint destruction in rheumatoid arthritis may require a concerted action of Th2 cytokines, Curr Opin Investig Drugs, 2002.

J. Van-roon, F. Lafeber, and J. Bijlsma, Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis, Arthritis & Rheumatism, vol.174, issue.1, 2001.
DOI : 10.1002/1529-0131(200101)44:1<3::AID-ANR2>3.0.CO;2-U

J. Van-roon, J. Van-roy, F. Gmelig-meyling, F. Lafeber, and J. Bijlsma, Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4. Arthritis Rheum, pp.829-864, 1996.

E. Varfolomeev, F. Kischkel, F. Martin, D. Seshasayee, H. Wang et al., APRIL-Deficient Mice Have Normal Immune System Development, Molecular and Cellular Biology, vol.24, issue.3, pp.997-1006, 2004.
DOI : 10.1128/MCB.24.3.997-1006.2004
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC321448

C. Verhoef, J. Van-roon, M. Vianen, C. Bruijnzeel-koomen, F. Lafeber et al., Mutual antagonism of rheumatoid arthritis and hay fever; a role for type 1/type 2??T cell balance, Annals of the Rheumatic Diseases, vol.57, issue.5, pp.275-80, 1998.
DOI : 10.1136/ard.57.5.275

G. Bülow and R. Bram, NF-AT Activation Induced by a CAML-Interacting Member of the Tumor Necrosis Factor Receptor Superfamily, Science, vol.278, issue.5335, pp.138-179, 1997.
DOI : 10.1126/science.278.5335.138

S. Wan, C. Xia, and L. Morel, IL-6 Produced by Dendritic Cells from Lupus-Prone Mice Inhibits CD4+CD25+ T Cell Regulatory Functions, The Journal of Immunology, vol.178, issue.1, pp.271-280, 2007.
DOI : 10.4049/jimmunol.178.1.271

H. Wang, S. Marsters, T. Baker, C. B. Lee, W. Fu et al., TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice, Nature Immunology, vol.2, issue.7, pp.632-639, 2001.
DOI : 10.1038/89782

C. Ware, The TNF superfamily. Cytokine Growth Factor Rev, pp.3-4181, 2003.
DOI : 10.1016/s1359-6101(03)00032-7

R. Williams, Rodent models of arthritis: relevance for human disease, Clinical and Experimental Immunology, vol.25, issue.3, 1998.
DOI : 10.1016/S0140-6736(89)90430-3

T. Williams and G. Granger, Lymphocyte in vitro Cytotoxicity: Lymphotoxins of Several Mammalian Species, Nature, vol.27, issue.5158, pp.1076-1083, 1968.
DOI : 10.1038/2191076a0

S. Wilson and T. Delovitch, Regulatory Lymphocytes: Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity, Nature Reviews Immunology, vol.3, issue.3, pp.211-233, 2003.
DOI : 10.1038/nri1028

P. Wooley, The usefulness and the limitations of animal models in identifying targets for therapy in arthritis, Best Practice & Research Clinical Rheumatology, vol.18, issue.1, pp.47-58, 2004.
DOI : 10.1016/j.berh.2003.09.007

H. Wu and N. Staines, A deficiency of CD4+ CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen, Lupus, vol.13, issue.3, pp.192-200, 2004.
DOI : 10.1191/0961203303lu1002oa

K. Yudoh, H. Matsuno, F. Nakazawa, T. Yonezawa, and T. Kimura, Reduced expression of the regulatory CD4+ T cell subset is related to Th1/Th2 balance and disease severity in rheumatoid arthritis, Arthritis & Rheumatism, vol.43, issue.3
DOI : 10.1002/1529-0131(200003)43:3<617::AID-ANR19>3.0.CO;2-B

D. Zeng, Y. Liu, S. Sidobre, M. Kronenberg, and S. Strober, Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus, Journal of Clinical Investigation, vol.112, issue.8, pp.1211-1233, 2003.
DOI : 10.1172/JCI200317165

S. Ziegler, FOXP3: Not just for regulatory T cells anymore, European Journal of Immunology, vol.177, issue.1, pp.21-24, 2007.
DOI : 10.1002/eji.200636929