Y. Aihara, H. Mashima, and H. Onda, Molecular Cloning of a Novel Brain-Type Na+-Dependent Inorganic Phosphate Cotransporter, Journal of Neurochemistry, vol.201, issue.6, pp.2622-2625, 2000.
DOI : 10.1046/j.1471-4159.2000.0742622.x

J. Almqvist, Y. Huang, A. Laaksonen, D. N. Wang, and S. Hovmoller, Docking and homology modeling explain inhibition of the human vesicular glutamate transporters, Protein Science, vol.91, issue.9, pp.1819-1829, 2007.
DOI : 10.1110/ps.072944707

B. Amilhon, E. Lepicard, and T. Renoir, soumis) VGLUT3 contribution to the regulation of serotoninergic transmission and anxiety

T. Arendt, V. Bigl, A. Arendt, and A. Tennstedt, Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease, Acta Neuropathologica, vol.II, issue.2, pp.101-108, 1983.
DOI : 10.1007/BF00697388

D. E. Arking, D. J. Cutler, and C. W. Brune, A Common Genetic Variant in the Neurexin Superfamily Member CNTNAP2 Increases Familial Risk of Autism, The American Journal of Human Genetics, vol.82, issue.1, pp.160-164, 2008.
DOI : 10.1016/j.ajhg.2007.09.015

J. L. Arriza, W. A. Fairman, J. I. Wadiche, G. H. Murdoch, M. P. Kavanaugh et al., Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex, J Neurosci, vol.14, pp.5559-5569, 1994.

G. A. Ascoli, L. Alonso-nanclares, and S. A. Anderson, Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex, Nature Reviews Neuroscience, vol.28, issue.7, pp.557-568, 2008.
DOI : 10.1038/nrn2402
URL : https://hal.archives-ouvertes.fr/hal-00292588

D. E. Baranano, C. D. Ferris, and S. H. Snyder, Atypical neural messengers, Trends in Neurosciences, vol.24, issue.2, pp.99-106, 2001.
DOI : 10.1016/S0166-2236(00)01716-1

K. F. Bell, C. Cuello, and A. , Altered synaptic function in Alzheimer's disease, European Journal of Pharmacology, vol.545, issue.1, pp.11-21, 2006.
DOI : 10.1016/j.ejphar.2006.06.045

E. E. Bellocchio, H. Hu, A. Pohorille, J. Chan, V. M. Pickel et al., The localization of the brain-specific inorganic phosphate transporter suggests a specific presynaptic role in glutamatergic transmission, J Neurosci, vol.18, pp.8648-8659, 1998.

E. E. Bellocchio, R. J. Reimer, R. T. Fremeau, . Jr, and R. H. Edwards, Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter, Science, vol.289, issue.5481, pp.957-960, 2000.
DOI : 10.1126/science.289.5481.957

Y. Ben-ari, Excitatory actions of gaba during development: the nature of the nurture, Nature Reviews Neuroscience, vol.3, issue.9, pp.728-739, 2002.
DOI : 10.1038/nrn920
URL : https://hal.archives-ouvertes.fr/inserm-00484852

V. Bergink, H. J. Van-megen, and H. G. Westenberg, Glutamate and anxiety, European Neuropsychopharmacology, vol.14, issue.3, pp.175-183, 2004.
DOI : 10.1016/S0924-977X(03)00100-7

C. Betancur, T. Sakurai, and J. D. Buxbaum, The emerging role of synaptic celladhesion pathways in the pathogenesis of autism spectrum disorders, Trends Neurosci, 2009.
URL : https://hal.archives-ouvertes.fr/inserm-00401195

K. W. Beyenbach and H. Wieczorek, The V-type H+ ATPase: molecular structure and function, physiological roles and regulation, Journal of Experimental Biology, vol.209, issue.4, pp.577-589, 2006.
DOI : 10.1242/jeb.02014

R. D. Blitzer, R. Iyengar, and E. M. Landau, Postsynaptic signaling networks: Cellular cogwheels underlying long-term plasticity, Biological Psychiatry, vol.57, issue.2, pp.113-119, 2005.
DOI : 10.1016/j.biopsych.2004.02.031

T. Bussiere, G. Gold, E. Kovari, P. Giannakopoulos, C. Bouras et al., Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer???s disease, Neuroscience, vol.117, issue.3, pp.577-592, 2003.
DOI : 10.1016/S0306-4522(02)00942-9

A. Camacho and L. Massieu, Role of Glutamate Transporters in the Clearance and Release of Glutamate during Ischemia and its Relation to Neuronal Death, Archives of Medical Research, vol.37, issue.1, pp.11-18, 2006.
DOI : 10.1016/j.arcmed.2005.05.014

M. D. Carlson, P. E. Kish, and T. Ueda, Glutamate Uptake into Synaptic Vesicles: Competitive Inhibition by Bromocriptine, Journal of Neurochemistry, vol.258, issue.6, pp.1889-1894, 1989.
DOI : 10.1146/annurev.pa.21.040181.001121

M. L. Carlsson, Hypothesis: Is infantile autism a hypoglutamatergic disorder? Relevance of glutamate ??? serotonin interactions for pharmacotherapy, Journal of Neural Transmission, vol.105, issue.4, pp.525-535, 1998.
DOI : 10.1007/s007020050076

M. Casado, P. Isope, and P. Ascher, Involvement of Presynaptic N-Methyl-D-Aspartate Receptors in Cerebellar Long-Term Depression, Neuron, vol.33, issue.1, pp.123-130, 2002.
DOI : 10.1016/S0896-6273(01)00568-2

A. G. Chapman, Glutamate and epilepsy, J Nutr, vol.130, pp.1043-1045, 2000.

K. R. Chaudhuri and A. H. Schapira, Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment, The Lancet Neurology, vol.8, issue.5, pp.464-474, 2009.
DOI : 10.1016/S1474-4422(09)70068-7

P. J. Conn and J. P. Pin, PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS, Annual Review of Pharmacology and Toxicology, vol.37, issue.1, pp.205-237, 1997.
DOI : 10.1146/annurev.pharmtox.37.1.205

J. F. Cryan and A. Holmes, Model organisms: The ascent of mouse: advances in modelling human depression and anxiety, Nature Reviews Drug Discovery, vol.11, issue.9, pp.775-790, 2005.
DOI : 10.1038/sj.npp.1300413

D. R. Curtis, J. W. Phillis, and J. C. Watkins, Chemical Excitation of Spinal Neurones, Nature, vol.182, issue.4661, pp.611-612, 1959.
DOI : 10.1038/183611a0

Y. Daikhin and M. Yudkoff, Compartmentation of brain glutamate metabolism in neurons and glia, J Nutr, vol.130, pp.1026-1031, 2000.

N. C. Danbolt, Glutamate uptake, Progress in Neurobiology, vol.65, issue.1, pp.1-105, 2001.
DOI : 10.1016/S0301-0082(00)00067-8

G. Daoudal and D. Debanne, Long-Term Plasticity of Intrinsic Excitability: Learning Rules and Mechanisms, Learning & Memory, vol.10, issue.6, pp.456-465, 2003.
DOI : 10.1101/lm.64103

D. Gois, S. Schafer, M. K. Defamie, N. Chen, C. Ricci et al., Homeostatic Scaling of Vesicular Glutamate and GABA Transporter Expression in Rat Neocortical Circuits, Journal of Neuroscience, vol.25, issue.31, pp.7121-7133, 2005.
DOI : 10.1523/JNEUROSCI.5221-04.2005

M. Desban, M. L. Kemel, J. Glowinski, and C. Gauchy, Spatial organization of patch and matrix compartments in the rat striatum, Neuroscience, vol.57, issue.3, pp.661-671, 1993.
DOI : 10.1016/0306-4522(93)90013-6

A. Doble, The Role of Excitotoxicity in Neurodegenerative Disease, Pharmacology & Therapeutics, vol.81, issue.3, pp.163-221, 1999.
DOI : 10.1016/S0163-7258(98)00042-4

G. Duncan, S. Miyamoto, H. Gu, J. Lieberman, B. Koller et al., Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function, Brain Research, vol.951, issue.2, pp.166-176, 2002.
DOI : 10.1016/S0006-8993(02)03156-6

C. M. Durand, C. Betancur, and T. M. Boeckers, Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders, Nature Genetics, vol.28, issue.1, pp.25-27, 2007.
DOI : 10.1038/ng1933
URL : https://hal.archives-ouvertes.fr/inserm-00126175

C. M. Durand, P. Chaste, F. Fauchereau, C. Betancur, M. Leboyer et al., [Alterations in synapsis formation and function in autism disorders, Med Sci, vol.24, pp.25-28, 2008.

L. E. Eiden, The vesicular neurotransmitter transporters: current perspectives and future prospects, The FASEB Journal, vol.14, issue.15, pp.2396-2400, 2000.
DOI : 10.1096/fj.00-0817rev

E. Sanchez, A. M. Mejia-toiber, J. Massieu, and L. , Excitotoxic Neuronal Death and the Pathogenesis of Huntington's Disease, Archives of Medical Research, vol.39, issue.3, pp.265-276, 2008.
DOI : 10.1016/j.arcmed.2007.11.011

W. A. Fairman, R. J. Vandenberg, J. L. Arriza, M. P. Kavanaugh, and S. G. Amara, An excitatory amino-acid transporter with properties of a ligand-gated chloride channel, Nature, vol.375, issue.6532, pp.599-603, 1995.
DOI : 10.1038/375599a0

S. M. Ferguson and R. D. Blakely, The Choline Transporter Resurfaces: New Roles for Synaptic Vesicles?, Molecular Interventions, vol.4, issue.1, pp.22-37, 2004.
DOI : 10.1124/mi.4.1.22

P. O. Fernagut, S. Chalon, E. Diguet, D. Guilloteau, F. Tison et al., Motor behaviour deficits and their histopathological and functional correlates in the nigrostriatal system of dopamine transporter knockout mice, Neuroscience, vol.116, issue.4, pp.1123-1130, 2003.
DOI : 10.1016/S0306-4522(02)00778-9

F. Fonnum, Glutamate: A Neurotransmitter in Mammalian Brain, Journal of Neurochemistry, vol.1, issue.1, pp.1-11, 1984.
DOI : 10.1016/0006-8993(74)91002-6

P. T. Francis, Glutamatergic systems in Alzheimer's disease, International Journal of Geriatric Psychiatry, vol.678, issue.S1, pp.15-21, 2003.
DOI : 10.1002/gps.934

R. T. Fremeau, . Jr, J. Burman, and T. Qureshi, The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate, Proceedings of the National Academy of Sciences, vol.99, issue.22, pp.14488-14493, 2002.
DOI : 10.1073/pnas.222546799

R. T. Fremeau, . Jr, M. D. Troyer, and I. Pahner, The Expression of Vesicular Glutamate Transporters Defines Two Classes of Excitatory Synapse, Neuron, vol.31, issue.2, pp.247-260, 2001.
DOI : 10.1016/S0896-6273(01)00344-0

R. T. Fremeau, . Jr, S. Voglmaier, R. P. Seal, and R. H. Edwards, VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate, Trends in Neurosciences, vol.27, issue.2, pp.98-103, 2004.
DOI : 10.1016/j.tins.2003.11.005

N. Froger, A. M. Gardier, and R. Moratalla, 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization, J Neurosci, vol.21, pp.8188-8197, 2001.

F. Fujiyama, T. Furuta, and T. Kaneko, Immunocytochemical localization of candidates for vesicular glutamate transporters in the rat cerebral cortex, The Journal of Comparative Neurology, vol.201, issue.3, pp.379-387, 2001.
DOI : 10.1002/cne.1037

E. M. Fykse and F. Fonnum, Transport of gamma-aminobutyrate and L-glutamate into synaptic vesicles. Effect of different inhibitors on the vesicular uptake of neurotransmitters and on the Mg2(+)-ATPase, Biochem J, issue.2, pp.276-363, 1991.

B. Gasnier, The loading of neurotransmitters into synaptic vesicles, Biochimie, vol.82, issue.4, pp.327-337, 2000.
DOI : 10.1016/S0300-9084(00)00221-2

D. H. Geschwind, Autism: Many Genes, Common Pathways?, Cell, vol.135, issue.3, pp.391-395, 2008.
DOI : 10.1016/j.cell.2008.10.016

C. Gras, B. Amilhon, and E. M. Lepicard, The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone, Nature Neuroscience, vol.28, issue.3, pp.292-300, 2008.
DOI : 10.1038/nn2052
URL : https://hal.archives-ouvertes.fr/hal-00263930

C. Gras, E. Herzog, G. C. Bellenchi, V. Bernard, P. Ravassard et al., A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons, J Neurosci, vol.22, pp.5442-5451, 2002.

J. Hartinger and R. Jahn, An anion binding site that regulates the glutamate transporter of synaptic vesicles, J Biol Chem, vol.268, pp.23122-23127, 1993.

J. W. Hell, P. R. Maycox, and R. Jahn, Energy dependence and functional reconstitution of the gamma-aminobutyric acid carrier from synaptic vesicles, J Biol Chem, vol.265, pp.2111-2117, 1990.

J. G. Hensler, Serotonergic modulation of the limbic system, Neuroscience & Biobehavioral Reviews, vol.30, issue.2, pp.203-214, 2006.
DOI : 10.1016/j.neubiorev.2005.06.007

N. Herrmann and S. Gauthier, Diagnosis and treatment of dementia: 6. Management of severe Alzheimer disease, Canadian Medical Association Journal, vol.179, issue.12, pp.1279-1287, 2008.
DOI : 10.1503/cmaj.070804

E. Herzog, G. C. Bellenchi, C. Gras, V. Bernard, P. Ravassard et al., The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons, J Neurosci, vol.21, p.181, 2001.

E. Herzog, J. Gilchrist, C. Gras, A. Muzerelle, P. Ravassard et al., Localization of VGLUT3, the vesicular glutamate transporter type 3, in the rat brain, Neuroscience, vol.123, issue.4, pp.983-1002, 2004.
DOI : 10.1016/j.neuroscience.2003.10.039

E. Herzog, M. Landry, and E. Buhler, Expression of vesicular glutamate transporters, VGLUT1 and VGLUT2, in cholinergic spinal motoneurons, European Journal of Neuroscience, vol.188, issue.7, pp.1752-1760, 2004.
DOI : 10.1016/0301-0082(96)00023-8

E. Herzog, S. Takamori, R. Jahn, N. Brose, and S. M. Wojcik, Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus, Journal of Neurochemistry, vol.279, issue.3, pp.1011-1018, 2006.
DOI : 10.1073/pnas.0401764101

H. Hioki, F. Fujiyama, K. Nakamura, S. X. Wu, W. Matsuda et al., Chemically Specific Circuit Composed of Vesicular Glutamate Transporter 3- and Preprotachykinin B-producing Interneurons in the Rat Neocortex, Cerebral Cortex, vol.14, issue.11, pp.1266-1275, 2004.
DOI : 10.1093/cercor/bhh088

J. E. Huettner, Kainate receptors and synaptic transmission, Progress in Neurobiology, vol.70, issue.5, pp.387-407, 2003.
DOI : 10.1016/S0301-0082(03)00122-9

C. P. Hughes, L. Berg, W. L. Danziger, L. A. Coben, and R. L. Martin, A new clinical scale for the staging of dementia, The British Journal of Psychiatry, vol.140, issue.6, pp.566-572, 1982.
DOI : 10.1192/bjp.140.6.566

A. Ikemoto, D. G. Bole, and T. Ueda, Glycolysis and Glutamate Accumulation into Synaptic Vesicles: ROLE OF GLYCERALDEHYDE PHOSPHATE DEHYDROGENASE AND 3-PHOSPHOGLYCERATE KINASE, Journal of Biological Chemistry, vol.278, issue.8, pp.5929-5940, 2003.
DOI : 10.1074/jbc.M211617200

J. Jackson, B. H. Bland, and M. C. Antle, Nonserotonergic projection neurons in the midbrain raphe nuclei contain the vesicular glutamate transporter VGLUT3, Synapse, vol.482, issue.3, Part 2, pp.31-41, 2009.
DOI : 10.1002/syn.20581

S. Jamain, C. Betancur, B. Giros, M. Leboyer, and T. Bourgeron, La g??n??tique de l???autisme, m??decine/sciences, vol.19, issue.11, pp.1081-1090, 2003.
DOI : 10.1051/medsci/200319111081

S. Jamain, H. Quach, and C. Betancur, Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism, Nature Genetics, vol.34, issue.1, pp.27-29, 2003.
DOI : 10.1038/ng1136
URL : https://hal.archives-ouvertes.fr/inserm-00124744

M. D. Johnson, Synaptic glutamate release by postnatal rat serotonergic neurons in microculture, Neuron, vol.12, issue.2, pp.433-442, 1994.
DOI : 10.1016/0896-6273(94)90283-6

N. Juge, Y. Yoshida, S. Yatsushiro, H. Omote, and Y. Moriyama, Vesicular Glutamate Transporter Contains Two Independent Transport Machineries, Journal of Biological Chemistry, vol.281, issue.51, pp.39499-39506, 2006.
DOI : 10.1074/jbc.M607670200

Y. Kanai and M. A. Hediger, Primary structure and functional characterization of a high-affinity glutamate transporter, Nature, vol.89, issue.6403, pp.467-471, 1992.
DOI : 10.1038/360467a0

T. Kaneko, H. Akiyama, I. Nagatsu, and N. Mizuno, Immunohistochemical demonstration of glutaminase in catecholaminergic and serotoninergic neurons of rat brain, Brain Research, vol.507, issue.1, pp.151-154, 1990.
DOI : 10.1016/0006-8993(90)90535-J

T. Kaneko and F. Fujiyama, Complementary distribution of vesicular glutamate transporters in the central nervous system, Neuroscience Research, vol.42, issue.4, pp.243-250, 2002.
DOI : 10.1016/S0168-0102(02)00009-3

A. Kashani, C. Betancur, B. Giros, E. Hirsch, E. Mestikawy et al., Altered expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in Parkinson disease, Neurobiology of Aging, vol.28, issue.4, pp.568-578, 2007.
DOI : 10.1016/j.neurobiolaging.2006.02.010
URL : https://hal.archives-ouvertes.fr/inserm-00154872

A. Kashani, E. Lepicard, and O. Poirel, Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease, Neurobiology of Aging, vol.29, issue.11, pp.1619-1630, 2008.
DOI : 10.1016/j.neurobiolaging.2007.04.010
URL : https://hal.archives-ouvertes.fr/inserm-00166908

Y. Kawaguchi, C. J. Wilson, S. J. Augood, and P. C. Emson, Striatal interneurones: chemical, physiological and morphological characterization, Trends in Neurosciences, vol.18, issue.12, pp.527-535, 1995.
DOI : 10.1016/0166-2236(95)98374-8

S. L. Kirvell, M. Esiri, and P. T. Francis, Down-regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease, Journal of Neurochemistry, vol.215, issue.3, pp.939-950, 2006.
DOI : 10.1016/0163-7258(93)90043-D

S. Lehericy, E. C. Hirsch, P. Cervera, L. B. Hersh, J. J. Hauw et al., Selective loss of cholinergic neurons in the ventral striatum of patients with Alzheimer disease., Proceedings of the National Academy of Sciences, vol.86, issue.21, pp.8580-8584, 1989.
DOI : 10.1073/pnas.86.21.8580

M. P. Martres, M. L. Bouthenet, N. Sales, P. Sokoloff, and J. C. Schwartz, Widespread distribution of brain dopamine receptors evidenced with [125I]iodosulpride, a highly selective ligand, Science, vol.228, issue.4700, pp.752-755, 1985.
DOI : 10.1126/science.3838821

J. Masson, C. Sagne, M. Hamon, E. Mestikawy, and S. , Neurotransmitter transporters in the central nervous system, Pharmacol Rev, vol.51, pp.439-464, 1999.

M. P. Mattson, Pathways towards and away from Alzheimer's disease, Nature, vol.22, issue.7000, pp.631-639, 2004.
DOI : 10.1016/j.molcel.2003.08.005

M. P. Mattson, Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease, Annals of the New York Academy of Sciences, vol.94, issue.Suppl., pp.97-112, 2008.
DOI : 10.1196/annals.1418.005

P. R. Maycox, T. Deckwerth, J. W. Hell, and R. Jahn, Glutamate uptake by brain synaptic vesicles. Energy dependence of transport and functional reconstitution in proteoliposomes, J Biol Chem, vol.263, pp.15423-15428, 1988.

P. R. Maycox, T. Deckwerth, and R. Jahn, Bacteriorhodopsin drives the glutamate transporter of synaptic vesicles after co-reconstitution, EMBO J, vol.9, pp.1465-1469, 1990.

P. R. Maycox and R. Jahn, Reconstitution of neurotransmitter carriers from synaptic vesicles, Biochemical Society Transactions, vol.18, issue.3, pp.381-384, 1990.
DOI : 10.1042/bst0180381

L. K. Medina-kauwe, N. J. Tillakaratne, J. Y. Wu, and A. J. Tobin, A Rat Brain cDNA Encodes Enzymatically Active GABA Transaminase and Provides a Molecular Probe for GABA-Catabolizing Cells, Journal of Neurochemistry, vol.3, issue.4, pp.1267-1275, 1994.
DOI : 10.1046/j.1471-4159.1994.62041267.x

B. S. Meldrum, Glutamate as a neurotransmitter in the brain: review of physiology and pathology, J Nutr, vol.130, pp.1007-1015, 2000.

A. Merighi, Costorage and coexistence of neuropeptides in the mammalian CNS, Progress in Neurobiology, vol.66, issue.3, pp.161-190, 2002.
DOI : 10.1016/S0301-0082(01)00031-4

J. Meunier and A. Shvaloff, Neurotransmetteurs -Bases neurobiologiques et pharmacologiques, p.161, 1992.

K. A. Michelsen, C. Schmitz, and H. W. Steinbusch, The dorsal raphe nucleus???From silver stainings to a role in depression, Brain Research Reviews, vol.55, issue.2, pp.329-342, 2007.
DOI : 10.1016/j.brainresrev.2007.01.002

T. Miyaji, N. Echigo, M. Hiasa, S. Senoh, H. Omote et al., Identification of a vesicular aspartate transporter, Proceedings of the National Academy of Sciences, vol.105, issue.33, pp.11720-11724, 2008.
DOI : 10.1073/pnas.0804015105

M. E. Molliver, Serotonergic Neuronal Systems, Journal of Clinical Psychopharmacology, vol.7, issue.Supplement 6, pp.3-23, 1987.
DOI : 10.1097/00004714-198712001-00002

H. Moreno-fuenmayor, L. Borjas, A. Arrieta, V. Valera, and L. Socorro-candanoza, Plasma excitatory amino acids in autism, Invest Clin, vol.37, pp.113-128, 1996.

S. Naito and T. Ueda, Adenosine triphosphate-dependent uptake of glutamate into protein I-associated synaptic vesicles, J Biol Chem, vol.258, pp.696-699, 1983.

S. Naito and T. Ueda, Characterization of Glutamate Uptake into Synaptic Vesicles, Journal of Neurochemistry, vol.56, issue.1, pp.99-109, 1985.
DOI : 10.1146/annurev.pa.21.040181.001121

K. Nakano, Neural circuits and topographic organization of the basal ganglia and related regions, Brain and Development, vol.22, issue.1, pp.5-16, 2000.
DOI : 10.1016/S0387-7604(00)00139-X

B. Ni, P. R. Rosteck, . Jr, N. S. Nadi, and S. M. Paul, Cloning and expression of a cDNA encoding a brain-specific Na(+)-dependent inorganic phosphate cotransporter., Proceedings of the National Academy of Sciences, vol.91, issue.12, pp.5607-5611, 1994.
DOI : 10.1073/pnas.91.12.5607

B. Ni, X. Wu, G. M. Yan, J. Wang, and S. M. Paul, Regional expression and cellular localization of the Na(+)-dependent inorganic phosphate cotransporter of rat brain, J Neurosci, vol.15, pp.5789-5799, 1995.

N. Poulin, A. Guerci, A. Mestikawy, S. Semba, and K. , Vesicular glutamate transporter 3 immunoreactivity is present in cholinergic basal forebrain neurons projecting to the basolateral amygdala in rat, The Journal of Comparative Neurology, vol.30, issue.5, pp.690-711, 2006.
DOI : 10.1002/cne.21081

K. Ogita, K. Hirata, D. G. Bole, S. Yoshida, Y. Tamura et al., Inhibition of vesicular glutamate storage and exocytotic release by Rose Bengal, J Neurochem, vol.77, pp.34-42, 2001.

O. P. Ottersen, F. A. Chaudhry, N. C. Danbolt, J. H. Laake, E. A. Nagelhus et al., Chapter 6 Molecular organization of cerebellar glutamate synapses, Prog Brain Res, vol.114, pp.97-107, 1997.
DOI : 10.1016/S0079-6123(08)63360-9

S. Ozawa, H. Kamiya, and K. Tsuzuki, Glutamate receptors in the mammalian central nervous system, Progress in Neurobiology, vol.54, issue.5, pp.581-618, 1998.
DOI : 10.1016/S0301-0082(97)00085-3

E. D. Ozkan, F. S. Lee, and T. Ueda, A protein factor that inhibits ATP-dependent glutamate and ??-aminobutyric acid accumulation into synaptic vesicles: Purification and initial characterization, Proceedings of the National Academy of Sciences, vol.94, issue.8, pp.4137-4142, 1997.
DOI : 10.1073/pnas.94.8.4137

E. D. Ozkan and T. Ueda, Glutamate transport and storage in synaptic vesicles, Jpn J Pharmacol, vol.77, pp.1-10, 1998.

S. M. Parsons, Transport mechanisms in acetylcholine and monoamine storage, The FASEB Journal, vol.14, issue.15, pp.2423-2434, 2000.
DOI : 10.1096/fj.00-0203rev

H. L. Payne, P. S. Donoghue, and W. M. Connelly, Aberrant GABAA Receptor Expression in the Dentate Gyrus of the Epileptic Mutant Mouse Stargazer, Journal of Neuroscience, vol.26, issue.33, pp.8600-8608, 2006.
DOI : 10.1523/JNEUROSCI.1088-06.2006

R. C. Pearson, M. M. Esiri, R. W. Hiorns, G. K. Wilcock, and T. P. Powell, Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease., Proceedings of the National Academy of Sciences, vol.82, issue.13, pp.4531-4534, 1985.
DOI : 10.1073/pnas.82.13.4531

D. C. Perry and K. J. Kellar, [3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study, J Pharmacol Exp Ther, vol.275, pp.1030-1034, 1995.

E. Perry, M. Walker, J. Grace, and R. Perry, Acetylcholine in mind: a neurotransmitter correlate of consciousness?, Trends in Neurosciences, vol.22, issue.6, pp.273-280, 1999.
DOI : 10.1016/S0166-2236(98)01361-7

G. Pines, N. C. Danbolt, and M. Bjoras, Cloning and expression of a rat brain L-glutamate transporter, Nature, vol.74, issue.6403, pp.464-467, 1992.
DOI : 10.1038/360464a0

P. S. Pinheiro and C. Mulle, Presynaptic glutamate receptors: physiological functions and mechanisms of action, Nature Reviews Neuroscience, vol.326, issue.6, pp.423-436, 2008.
DOI : 10.1038/nrn2379

A. E. Purcell, O. H. Jeon, A. W. Zimmerman, M. E. Blue, and J. Pevsner, Postmortem brain abnormalities of the glutamate neurotransmitter system in autism, Neurology, vol.57, issue.9, pp.1618-1628, 2001.
DOI : 10.1212/WNL.57.9.1618

D. Purves, S. M. Williams, S. Nundy, and R. B. Lotto, Perceiving the Intensity of Light., Psychological Review, vol.111, issue.1, pp.142-158, 2004.
DOI : 10.1037/0033-295X.111.1.142

M. Que, O. W. Witte, T. Neumann-haefelin, K. Schiene, M. Schroeter et al., Changes in GABAA and GABAB receptor binding following cortical photothrombosis: a quantitative receptor autoradiographic study, Neuroscience, vol.93, issue.4, pp.1233-1240, 1999.
DOI : 10.1016/S0306-4522(99)00197-9

R. J. Reimer, R. T. Fremeau, . Jr, E. E. Bellocchio, and R. H. Edwards, The essence of excitation, Current Opinion in Cell Biology, vol.13, issue.4, pp.417-421, 2001.
DOI : 10.1016/S0955-0674(00)00230-1

A. Rodriguez-moreno and T. S. Sihra, Metabotropic actions of kainate receptors in the CNS, Journal of Neurochemistry, vol.266, issue.6, pp.2121-2135, 2007.
DOI : 10.1073/pnas.89.9.4134

L. H. Rolf, F. Y. Haarmann, K. H. Grotemeyer, and H. Kehrer, Serotonin and amino acid content in platelets of autistic children, Acta Psychiatrica Scandinavica, vol.53, issue.5, pp.312-316, 1993.
DOI : 10.1111/j.1471-4159.1981.tb01701.x

S. Roseth, E. M. Fykse, and F. Fonnum, Uptake of l-Glutamate into Rat Brain Synaptic Vesicles: Effect of Inhibitors that Bind Specifically to the Glutamate Transporter, Journal of Neurochemistry, vol.65, issue.1, pp.96-103, 1995.
DOI : 10.1046/j.1471-4159.1995.65010096.x

S. Roseth, E. M. Fykse, and F. Fonnum, Uptake of l-glutamate into synaptic vesicles: competitive inhibition by dyes with biphenyl and amino- and sulphonic acid-substituted naphthyl groups, Biochemical Pharmacology, vol.56, issue.9, pp.1243-1249, 1998.
DOI : 10.1016/S0006-2952(98)00200-7

R. Rupprecht, F. Di-michele, B. Hermann, A. Strohle, M. Lancel et al., Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacology, Brain Research Reviews, vol.37, issue.1-3, pp.59-67, 2001.
DOI : 10.1016/S0165-0173(01)00123-0

C. Sagne, S. Mestikawy, M. F. Isambert, M. Hamon, J. P. Henry et al., Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases, FEBS Letters, vol.104, issue.2, pp.177-183, 1997.
DOI : 10.1016/S0014-5793(97)01279-9

S. Sahai, Glutamate in the mammalian CNS, European Archives of Psychiatry and Clinical Neuroscience, vol.81, issue.Suppl, pp.121-133, 1990.
DOI : 10.1007/BF02189982

S. Y. Sakurai, P. L. Lutz, A. Schulman, and R. L. Albin, Unchanged [3H]MK-801 binding and increased [3H]flunitrazepam binding in turtle forebrain during anoxia, Brain Research, vol.625, issue.2, pp.181-185, 1993.
DOI : 10.1016/0006-8993(93)91057-Y

C. Salio, L. Lossi, F. Ferrini, and A. Merighi, Neuropeptides as synaptic transmitters, Cell and Tissue Research, vol.133, issue.Suppl 1, pp.583-598, 2006.
DOI : 10.1007/s00441-006-0268-3

M. Sarter and V. Parikh, Choline transporters, cholinergic transmission and cognition, Nature Reviews Neuroscience, vol.30, issue.1, pp.48-56, 2005.
DOI : 10.1038/nrn1588

K. Sawada, N. Echigo, N. Juge, T. Miyaji, M. Otsuka et al., Identification of a vesicular nucleotide transporter, Proceedings of the National Academy of Sciences, vol.105, issue.15, pp.5683-5686, 2008.
DOI : 10.1073/pnas.0800141105

M. K. Schafer, H. Varoqui, N. Defamie, E. Weihe, and J. D. Erickson, Molecular Cloning and Functional Identification of Mouse Vesicular Glutamate Transporter 3 and Its Expression in Subsets of Novel Excitatory Neurons, Journal of Biological Chemistry, vol.277, issue.52, pp.50734-50748, 2002.
DOI : 10.1074/jbc.M206738200

S. M. Schmid and M. Hollmann, To Gate or not to Gate: Are the Delta Subunits in the Glutamate Receptor Family Functional Ion Channels?, Molecular Neurobiology, vol.350, issue.1, pp.126-141, 2008.
DOI : 10.1007/s12035-008-8025-0

J. Schwartz, H (2000) Neurotransmetters. Principles of Neural Science, pp.280-297

R. P. Seal, O. Akil, and E. Yi, Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3, Neuron, vol.57, issue.2, pp.263-275, 2008.
DOI : 10.1016/j.neuron.2007.11.032

R. S. Shah, H. G. Lee, Z. Xiongwei, G. Perry, M. A. Smith et al., Current approaches in the treatment of Alzheimer's disease, Biomedicine & Pharmacotherapy, vol.62, issue.4, pp.199-207, 2008.
DOI : 10.1016/j.biopha.2008.02.005

J. Somogyi, A. Baude, Y. Omori, H. Shimizu, S. Mestikawy et al., GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat, European Journal of Neuroscience, vol.238, issue.3, pp.552-569, 2004.
DOI : 10.1016/S0169-328X(96)00209-4

D. P. Spurden, J. A. Court, S. Lloyd, A. Oakley, R. Perry et al., Nicotinic receptor distribution in the human thalamus: autoradiographical localization of [3H]nicotine and [125I]??-bungarotoxin binding, Journal of Chemical Neuroanatomy, vol.13, issue.2, pp.105-113, 1997.
DOI : 10.1016/S0891-0618(97)00038-0

G. D. Stanwood, R. P. Artymyshyn, M. P. Kung, H. F. Kung, I. Lucki et al., Quantitative autoradiographic mapping of rat brain dopamine D3 binding with [(125)I]7-OH-PIPAT: evidence for the presence of D3 receptors on dopaminergic and nondopaminergic cell bodies and terminals, J Pharmacol Exp Ther, vol.295, pp.1223-1231, 2000.

T. Storck, S. Schulte, K. Hofmann, and W. Stoffel, Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain., Proceedings of the National Academy of Sciences, vol.89, issue.22, pp.10955-10959, 1992.
DOI : 10.1073/pnas.89.22.10955

J. Storm-mathisen and L. L. Iversen, Uptake of [3H]glutamic acid in excitatory nerve endings: Light and electronmicroscopic observations in the hippocampal formation of the rat, Neuroscience, vol.4, issue.9, pp.1237-1253, 1979.
DOI : 10.1016/0306-4522(79)90154-4

J. Storm-mathisen, A. K. Leknes, A. T. Bore, J. L. Vaaland, P. Edminson et al., First visualization of glutamate and GABA in neurones by immunocytochemistry, Nature, vol.15, issue.5900, pp.517-520, 1983.
DOI : 10.1038/301517a0

J. Storm-mathisen and O. P. Ottersen, Immunocytochemistry of glutamate at the synaptic level., Journal of Histochemistry & Cytochemistry, vol.38, issue.12, pp.1733-1743, 1990.
DOI : 10.1177/38.12.1979340

J. S. Tabb, P. E. Kish, R. Van-dyke, and T. Ueda, Glutamate transport into synaptic vesicles. Roles of membrane potential, pH gradient, and intravesicular pH, J Biol Chem, vol.267, pp.15412-15418, 1992.

M. Takahashi, B. Billups, D. Rossi, M. Sarantis, M. Hamann et al., The role of glutamate transporters in glutamate homeostasis in the brain, J Exp Biol, vol.200, pp.401-409, 1997.

S. Takamori, P. Malherbe, C. Broger, and R. Jahn, Molecular cloning and functional characterization of human vesicular glutamate transporter 3, EMBO Reports, vol.3, issue.8, pp.798-803, 2002.
DOI : 10.1093/embo-reports/kvf159

S. Takamori, J. S. Rhee, C. Rosenmund, and R. Jahn, Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons, Nature, vol.407, pp.189-194, 2000.

S. Takamori, J. S. Rhee, C. Rosenmund, and R. Jahn, Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2), J Neurosci, vol.21, p.182, 2001.

L. T. Tien, L. W. Fan, C. Sogawa, T. Ma, H. H. Loh et al., Changes in acetylcholinesterase activity and muscarinic receptor bindings in ??-opioid receptor knockout mice, Molecular Brain Research, vol.126, issue.1, pp.38-44, 2004.
DOI : 10.1016/j.molbrainres.2004.03.011

M. R. Turner, M. C. Kiernan, P. N. Leigh, and K. Talbot, Biomarkers in amyotrophic lateral sclerosis, The Lancet Neurology, vol.8, issue.1, pp.94-109, 2009.
DOI : 10.1016/S1474-4422(08)70293-X

F. Varoqueaux, G. Aramuni, R. L. Rawson, R. Mohrmann, M. Missler et al., Neuroligins Determine Synapse Maturation and Function, Neuron, vol.51, issue.6, pp.741-754, 2006.
DOI : 10.1016/j.neuron.2006.09.003

F. Varoqueaux, S. Jamain, and N. Brose, Neuroligin 2 is exclusively localized to inhibitory synapses, European Journal of Cell Biology, vol.83, issue.9, pp.449-456, 2004.
DOI : 10.1078/0171-9335-00410

H. Varoqui, M. K. Schafer, H. Zhu, E. Weihe, and J. D. Erickson, Identification of the differentiation-associated Na+/PI transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses, J Neurosci, vol.22, pp.142-155, 2002.

P. Voorn, L. J. Vanderschuren, H. J. Groenewegen, T. W. Robbins, and C. M. Pennartz, Putting a spin on the dorsal???ventral divide of the striatum, Trends in Neurosciences, vol.27, issue.8, pp.468-474, 2004.
DOI : 10.1016/j.tins.2004.06.006

A. Wallen-mackenzie, H. Gezelius, M. Thoby-brisson, A. Nygard, A. Enjin et al., Vesicular Glutamate Transporter 2 Is Required for Central Respiratory Rhythm Generation But Not for Locomotor Central Pattern Generation, Journal of Neuroscience, vol.26, issue.47, pp.12294-12307, 2006.
DOI : 10.1523/JNEUROSCI.3855-06.2006
URL : https://hal.archives-ouvertes.fr/hal-00116157

M. Waselus, J. P. Galvez, R. J. Valentino, and E. J. Van-bockstaele, Differential projections of dorsal raphe nucleus neurons to the lateral septum and striatum, Journal of Chemical Neuroanatomy, vol.31, issue.4, pp.233-242, 2006.
DOI : 10.1016/j.jchemneu.2006.01.007

J. C. Watkins, l-Glutamate as a Central Neurotransmitter: Looking Back, Biochemical Society Transactions, vol.28, issue.4, pp.297-309, 2000.
DOI : 10.1042/bst0280297

R. I. Westphalen, H. L. Scott, and P. R. Dodd, Synaptic vesicle transport and synaptic membrane transporter sites in excitatory amino acid nerve terminals in Alzheimer disease, Journal of Neural Transmission, vol.110, issue.9, pp.1013-1027, 2003.
DOI : 10.1007/s00702-003-0012-z

S. M. Wojcik, J. S. Rhee, E. Herzog, A. Sigler, R. Jahn et al., An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size, Proceedings of the National Academy of Sciences, vol.101, issue.18, pp.7158-7163, 2004.
DOI : 10.1073/pnas.0401764101

H. Wolosker, D. O. De-souza, and L. De-meis, Regulation of Glutamate Transport into Synaptic Vesicles by Chloride and Proton Gradient, Journal of Biological Chemistry, vol.271, issue.20, pp.11726-11731, 1996.
DOI : 10.1074/jbc.271.20.11726

F. M. Zhou, C. J. Wilson, and J. A. Dani, Cholinergic interneuron characteristics and nicotinic properties in the striatum, Journal of Neurobiology, vol.4, issue.4, pp.590-605, 2002.
DOI : 10.1002/neu.10150