H. Hmg-coa, Hydroxy-Méthyl-Glutaryl Co-enzyme A ICAM-1: Intracellular Adhesion Molecule IFN-g: Interféron-gamma Ig: Immunoglobuline IL: Interleukine IPP: Isopentenyl Pyrophosphate LB: Lymphocytes B LFA: Lymphocyte Function-Associated Antigen-1 LPS: Lipopolysaccharide LT: Lymphocytes T M.BCG: mycobacterium bovis BCG M.tub: Mycobacterium tuberculosis MICA: CMH-I, HLA: Human Leukocytes Antigen HMBPP: voir NK: Natural Killer NKR: Natural Killer Receptor NKT: Natural Killer T cell Pam: Pamidronate PAMPs: Pathogen Associated Molecular Patterns PBMC: Peripheral Blood Mononuclear Cells PC5: Phycoérythrine-Cyanine 5

M. L. Albert and S. F. Pearce, and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes, The Journal of Experimental Medicine, vol.265, issue.7, pp.1359-68, 1998.
DOI : 10.1126/science.270.5241.1500

URL : https://hal.archives-ouvertes.fr/pasteur-01402441

T. J. Allison and C. C. Winter, Structure of a human ???? T-cell antigen receptor, Nature, vol.411, issue.6839, pp.820-824, 2001.
DOI : 10.1038/35081115

C. Arnaud and N. R. Veillard, Cholesterol-independent Effects of Statins in Inflammation, Immunomodulation and Atherosclerosis, Current Drug Target -Cardiovascular & Hematological Disorders, vol.5, issue.2, pp.127-161, 2005.
DOI : 10.2174/1568006043586198

D. V. Banthorpe and B. V. Charlwood, Biosynthesis of monoterpenes, Chemical Reviews, vol.72, issue.2, pp.115-55, 1972.
DOI : 10.1021/cr60276a002

S. Bauer and V. Groh, Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA, Science, vol.285, issue.5428, pp.727-736, 1999.
DOI : 10.1126/science.285.5428.727

A. Bendelac and M. Bonneville, AUTOREACTIVITY BY DESIGN: INNATE B AND T LYMPHOCYTES, Nature Reviews Immunology, vol.163, issue.3, pp.177-86, 2001.
DOI : 10.1038/35097097

M. Bonneville and E. Scotet, Human V??9V??2 T cells: promising new leads for immunotherapy of infections and tumors, Current Opinion in Immunology, vol.18, issue.5, pp.539-585, 2006.
DOI : 10.1016/j.coi.2006.07.002

W. H. Boom, ???? T cells and Mycobacterium tuberculosis, Microbes and Infection, vol.1, issue.3, pp.187-95, 1999.
DOI : 10.1016/S1286-4579(99)80033-1

P. Bousso and E. Robey, Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes, Nature Immunology, vol.4, issue.6, pp.579-85, 2003.
DOI : 10.1038/ni928

M. Brandes and K. Willimann, Flexible migration program regulates ???? T-cell involvement in humoral immunity, Blood, vol.102, issue.10, pp.3693-701, 2003.
DOI : 10.1182/blood-2003-04-1016

M. Brandes and K. Willimann, Professional Antigen-Presentation Function by Human gd T Cells, Science, vol.309, issue.5732, pp.264-272, 2005.
DOI : 10.1126/science.1110267

J. F. Bukowski and C. T. Morita, V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer, J Immunol, vol.154, issue.3, pp.998-1006, 1995.

N. Caccamo and G. Sireci, gammadelta T cells condition dendritic cells in vivo for priming pulmonary CD8 T cell responses against Mycobacterium tuberculosis, Eur J Immunol, 2006.

Z. W. Chen, Immune regulation of ???? T cell responses in mycobacterial infections, Clinical Immunology, vol.116, issue.3, pp.202-209, 2005.
DOI : 10.1016/j.clim.2005.04.005

A. Chow and D. Toomre, Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane, Nature, vol.7, issue.6901, pp.988-94, 2002.
DOI : 10.1084/JEM.20011543

P. Constant and F. Davodeau, Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands, Science, vol.264, issue.5156, pp.267-70, 1994.
DOI : 10.1126/science.8146660

P. Constant and Y. Poquet, The antituberculous Mycobacterium bovis BCG vaccine is an attenuated mycobacterial producer of phosphorylated nonpeptidic antigens for human gamma delta T cells, Infect Immun, vol.63, issue.12, pp.4628-4661, 1995.

L. Conti and R. Casetti, Reciprocal Activating Interaction Between Dendritic Cells and Pamidronate-Stimulated ???? T Cells: Role of CD86 and Inflammatory Cytokines, The Journal of Immunology, vol.174, issue.1, pp.252-60, 2005.
DOI : 10.4049/jimmunol.174.1.252

M. Corvaisier and A. Moreau-aubry, V??9V??2 T Cell Response to Colon Carcinoma Cells, The Journal of Immunology, vol.175, issue.8, pp.5481-5489, 2005.
DOI : 10.4049/jimmunol.175.8.5481

L. Dagna and A. Iellem, Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 ??????? T lymphocytes, European Journal of Immunology, vol.32, issue.10, pp.2934-2977, 2002.
DOI : 10.1002/1521-4141(2002010)32:10<2934::AID-IMMU2934>3.0.CO;2-6

J. E. Dalton and G. Howell, Fas-Fas Ligand Interactions Are Essential for the Binding to and Killing of Activated Macrophages by ???? T Cells, The Journal of Immunology, vol.173, issue.6, pp.3660-3667, 2004.
DOI : 10.4049/jimmunol.173.6.3660

H. Das and M. Sugita, Mechanisms of V??1 ???? T Cell Activation by Microbial Components, The Journal of Immunology, vol.172, issue.11, pp.6578-86, 2004.
DOI : 10.4049/jimmunol.172.11.6578

C. A. Daubenberger and M. Salomon, Functional and Structural Similarity of V??9V??2 T Cells in Humans and Aotus Monkeys, a Primate Infection Model for Plasmodium falciparum Malaria, The Journal of Immunology, vol.167, issue.11, pp.6421-6451, 2001.
DOI : 10.4049/jimmunol.167.11.6421

F. Davodeau and M. A. Peyrat, Close correlation between Daudi and mycobacterial antigen recognition by human gamma delta T cells and expression of V9JPC1 gamma/V2DJC delta-encoded T cell receptors, J Immunol, vol.151, issue.3, pp.1214-1237, 1993.

D. Libero, G. , and G. Casorati, Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells, Journal of Experimental Medicine, vol.173, issue.6, pp.1311-1333, 1991.
DOI : 10.1084/jem.173.6.1311

D. Fabrizio, L. , and Y. Kimura, Specific triggering of gamma, delta T cells by K562 activates the gamma, delta T cell receptor and may regulate natural killer-like function, J Immunol, vol.146, issue.8, pp.2495-503, 1991.

F. Dieli and J. Ivanyi, Characterization of Lung ???? T Cells Following Intranasal Infection with Mycobacterium bovis Bacillus Calmette-Guerin, The Journal of Immunology, vol.170, issue.1, pp.463-472, 2003.
DOI : 10.4049/jimmunol.170.1.463

F. Dieli and F. Poccia, Differentiation of Effector/Memory V??2 T Cells and Migratory Routes in Lymph Nodes or Inflammatory Sites, The Journal of Experimental Medicine, vol.157, issue.3, pp.391-398, 2003.
DOI : 10.1086/345766

F. Dieli and M. Troye-blomberg, V??9 / V??2 T lymphocytes reduce the viability of intracellularMycobacterium tuberculosis, European Journal of Immunology, vol.30, issue.5, pp.1512-1521, 2000.
DOI : 10.1002/(SICI)1521-4141(200005)30:5<1512::AID-IMMU1512>3.0.CO;2-3

F. Dieli and M. Troye-blomberg, by V??9/V??2 T Lymphocytes, The Journal of Infectious Diseases, vol.184, issue.8, pp.1082-1087, 2001.
DOI : 10.1086/323600

P. A. Edwards and J. Ericsson, Sterols and Isoprenoids: Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway, Annual Review of Biochemistry, vol.68, issue.1, pp.157-85, 1999.
DOI : 10.1146/annurev.biochem.68.1.157

E. Espinosa and C. Belmant, Chemical Synthesis and Biological Activity of Bromohydrin Pyrophosphate, a Potent Stimulator of Human gamma delta T Cells, Journal of Biological Chemistry, vol.276, issue.21, pp.18337-18381, 2001.
DOI : 10.1074/jbc.M100495200

E. Espinosa and C. Belmant, Y2K+1 state-of-the-art on non-peptide phosphoantigens, a novel category of immunostimulatory molecules, Microbes and Infection, vol.3, issue.8, pp.645-54, 2001.
DOI : 10.1016/S1286-4579(01)01420-4

E. Espinosa and J. Tabiasco, Synaptic Transfer by Human ???? T Cells Stimulated with Soluble or Cellular Antigens, The Journal of Immunology, vol.168, issue.12, pp.6336-6379, 2002.
DOI : 10.4049/jimmunol.168.12.6336

B. Favier and E. Espinosa, Uncoupling between Immunological Synapse Formation and Functional Outcome in Human ???? T Lymphocytes, The Journal of Immunology, vol.171, issue.10, pp.5027-5060, 2003.
DOI : 10.4049/jimmunol.171.10.5027

C. G. Feng and A. G. Bean, Increase in gamma interferon-secreting CD8(+), as well as CD4(+), T cells in lungs following aerosol infection with Mycobacterium tuberculosis, Infect Immun, vol.67, issue.7, pp.3242-3249, 1999.

P. Fisch and M. Malkovsky, Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt's lymphoma cells, Science, vol.250, issue.4985, pp.1269-73, 1990.
DOI : 10.1126/science.1978758

K. Fischer and E. Scotet, Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells, Proceedings of the National Academy of Sciences, vol.101, issue.29, pp.10685-90, 2004.
DOI : 10.1073/pnas.0403787101

S. Fujii and K. Liu, The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation, The Journal of Experimental Medicine, vol.162, issue.12, pp.1607-1625, 2004.
DOI : 10.4049/jimmunol.167.11.6247

M. C. Gagliardi and R. Teloni, Mycobacterium bovis Bacillus Calmette-Guerin infects DC-SIGN- dendritic cell and causes the inhibition of IL-12 and the enhancement of IL-10 production, Journal of Leukocyte Biology, vol.78, issue.1, pp.106-119, 2005.
DOI : 10.1189/jlb.0105037

K. C. Garcia and L. Teyton, STRUCTURAL BASIS OF T CELL RECOGNITION, Annual Review of Immunology, vol.17, issue.1, pp.369-97, 1999.
DOI : 10.1146/annurev.immunol.17.1.369

J. Geginat and F. Sallusto, T Cells, The Journal of Experimental Medicine, vol.162, issue.12, pp.1711-1720, 2001.
DOI : 10.1016/S0167-5699(99)01510-8

T. B. Geijtenbeek, S. J. Van, and . Vliet, Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function, The Journal of Experimental Medicine, vol.93, issue.1, pp.7-17, 2003.
DOI : 10.1084/jem.192.9.1213

A. V. Gett and F. Sallusto, T cell fitness determined by signal strength, Nature Immunology, vol.4, issue.4, pp.355-60, 2003.
DOI : 10.1038/ni908

H. J. Gober and M. Kistowska, Human T Cell Receptor ???? Cells Recognize Endogenous Mevalonate Metabolites in Tumor Cells, The Journal of Experimental Medicine, vol.263, issue.2, pp.163-171, 2003.
DOI : 10.1038/sj.onc.1203002

V. Groh and S. Porcelli, Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system, Journal of Experimental Medicine, vol.169, issue.4, pp.1277-94, 1989.
DOI : 10.1084/jem.169.4.1277

F. Halary and M. A. Peyrat, Control of self-reactive cytotoxic T lymphocytes expressing ???? T cell receptors by natural killer inhibitory receptors, European Journal of Immunology, vol.365, issue.11, pp.2812-2833, 1997.
DOI : 10.1002/eji.1830271111

W. A. Hanekom and M. Mendillo, Inhibits Maturation of Human Monocyte???Derived Dendritic Cells In Vitro, The Journal of Infectious Diseases, vol.188, issue.2, pp.257-66, 2003.
DOI : 10.1086/376451

T. Hara and Y. Mizuno, Predominant activation and expansion of V gamma 9-bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection., Journal of Clinical Investigation, vol.90, issue.1, pp.204-214, 1992.
DOI : 10.1172/JCI115837

A. C. Hayday, ???? Cells: A Right Time and a Right Place for a Conserved Third Way of Protection, Annual Review of Immunology, vol.18, issue.1, pp.975-1026, 2000.
DOI : 10.1146/annurev.immunol.18.1.975

R. A. Henderson and S. C. Watkins, Activation of human dendritic cells following infection with Mycobacterium tuberculosis, J Immunol, vol.159, issue.2, pp.635-678, 1997.

I. F. Hermans and J. D. Silk, NKT Cells Enhance CD4+ and CD8+ T Cell Responses to Soluble Antigen In Vivo through Direct Interaction with Dendritic Cells, The Journal of Immunology, vol.171, issue.10, pp.5140-5147, 2003.
DOI : 10.4049/jimmunol.171.10.5140

R. E. Hewitt and A. Lissina, The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins, Clinical and Experimental Immunology, vol.19, issue.1, pp.101-112, 2005.
DOI : 10.1038/13476

Z. Hmama and R. Gabathuler, Attenuation of HLA-DR expression by mononuclear phagocytes infected with Mycobacterium tuberculosis is related to intracellular sequestration of immature class II heterodimers, J Immunol, vol.161, issue.9, pp.4882-93, 1998.

M. Ho and H. K. Webster, Increased gamma delta T cells in acute Plasmodium falciparum malaria, Immunol Lett, vol.25, pp.1-3, 1990.

D. F. Hoft and R. M. Brown, Bacille Calmette-Guerin vaccination enhances human gamma delta T cell responsiveness to mycobacteria suggestive of a memory-like phenotype, J Immunol, vol.161, issue.2, pp.1045-54, 1998.

J. Holoshitz and F. Koning, Isolation of CD4-CD8-mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid, Nature, vol.339, issue.6221, pp.226-235, 1989.
DOI : 10.1038/339226a0

J. Ismaili and V. Olislagers, Human gamma delta T cells induce dendritic cell maturation, Clin Immunol, vol.1033, pp.296-302, 2002.

X. Jiao and R. Lo-man, Dendritic Cells Are Host Cells for Mycobacteria In Vivo That Trigger Innate and Acquired Immunity, The Journal of Immunology, vol.168, issue.3, pp.1294-301, 2002.
DOI : 10.4049/jimmunol.168.3.1294

F. Jouen-beades and E. Paris, In vivo and in vitro activation and expansion of gammadelta T cells during Listeria monocytogenes infection in humans, Infect Immun, vol.65, issue.10, pp.4267-72, 1997.

D. Kabelitz and A. Bender, A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein, Journal of Experimental Medicine, vol.171, issue.3, pp.667-79, 1990.
DOI : 10.1084/jem.171.3.667

D. Kabelitz and T. Hinz, Clonal expansion of Vgamma3/Vdelta3-expressing gammadelta T cells in an HIV-1/2-negative patient with CD4 T-cell deficiency, British Journal of Haematology, vol.96, issue.2, pp.266-71, 1997.
DOI : 10.1046/j.1365-2141.1997.d01-2027.x

A. B. Kamath and L. Wang, Antigens in tea-beverage prime human V??2V??2 T cells in vitro and in vivo for memory and nonmemory antibacterial cytokine responses, Proceedings of the National Academy of Sciences, vol.100, issue.10, pp.6009-6023, 2003.
DOI : 10.1073/pnas.1035603100

Y. Kato and Y. Tanaka, Requirement of Species-Specific Interactions for the Activation of Human ???? T Cells by Pamidronate, The Journal of Immunology, vol.170, issue.7, pp.3608-3621, 2003.
DOI : 10.4049/jimmunol.170.7.3608

S. H. Kaufmann and U. E. Schaible, A Dangerous Liaison between Two Major Killers: Figure 1., The Journal of Experimental Medicine, vol.71, issue.1, pp.1-5, 2003.
DOI : 10.1034/j.1600-0854.2000.010306.x

T. Kawai and S. Akira, Pathogen recognition with Toll-like receptors, Current Opinion in Immunology, vol.17, issue.4, pp.338-382, 2005.
DOI : 10.1016/j.coi.2005.02.007

M. Kroca and A. Johansson, V gamma 9V delta 2 T cells in human legionellosis, Clin Diagn Lab Immunol, vol.8, issue.5, pp.949-54, 2001.

V. Lafont and J. Liautard, Isopentenyl Pyrophosphate, a Mycobacterial Non-peptidic Antigen, Triggers Delayed and Highly Sustained Signaling in Human ???? T Lymphocytes without Inducing Down-modulation of T Cell Antigen Receptor, Journal of Biological Chemistry, vol.276, issue.19, pp.15961-15968, 2001.
DOI : 10.1074/jbc.M008684200

X. Lai and Y. Shen, Immune biology of macaque lymphocyte populations during mycobacterial infection, Clinical and Experimental Immunology, vol.168, issue.158, pp.182-92, 2003.
DOI : 10.1002/1521-4141(199801)28:01<104::AID-IMMU104>3.0.CO;2-F

F. Lang and M. A. Peyrat, Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands, J Immunol, vol.154, issue.11, pp.5986-94, 1995.

J. A. Langermans and P. Andersen, Divergent effect of bacillus Calmette-Guerin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: Implications for primate models in tuberculosis vaccine research, Proceedings of the National Academy of Sciences, vol.98, issue.20, pp.98-11497, 2001.
DOI : 10.1073/pnas.201404898

L. L. Lanier and J. Ruitenberg, Structural and serological heterogeneity of ??/?? T cell antigen receptor expression in thymus and peripherar blood, European Journal of Immunology, vol.331, issue.12, pp.1985-92, 1988.
DOI : 10.1002/eji.1830181218

D. S. Leslie and M. S. Vincent, CD1-mediated ??/?? T Cell Maturation of Dendritic Cells, The Journal of Experimental Medicine, vol.143, issue.4, pp.1575-84, 2002.
DOI : 10.1006/clim.2002.5218

B. Li and M. D. Rossman, Disease-specific changes in gammadelta T cell repertoire and function in patients with pulmonary tuberculosis, J Immunol, vol.157, issue.9, pp.4222-4231, 1996.

F. Mami-chouaib and C. Flament, TCRAlpha/Beta and TCRGamma/Delta CD4??? /CD8??? HLA-DR alloreactive CTL clones do not use fas/fas ligand pathway to lyse their specific target cells, Human Immunology, vol.51, issue.1, pp.13-22, 1996.
DOI : 10.1016/S0198-8859(96)00164-4

C. Martin and A. Williams, The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs, Vaccine, vol.24, issue.17, pp.3408-3427, 2006.
DOI : 10.1016/j.vaccine.2006.03.017

P. Matzinger, The Danger Model: A Renewed Sense of Self, Science, vol.296, issue.5566, pp.301-306, 2002.
DOI : 10.1126/science.1071059

T. K. Means and S. Wang, Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis, J Immunol, vol.163, issue.7, pp.3920-3927, 1999.

N. Meissner and J. Radke, Serial Analysis of Gene Expression in Circulating ???? T Cell Subsets Defines Distinct Immunoregulatory Phenotypes and Unexpected Gene Expression Profiles, The Journal of Immunology, vol.170, issue.1, pp.356-64, 2003.
DOI : 10.4049/jimmunol.170.1.356

T. R. Mempel and S. E. Henrickson, T-cell priming by dendriticcells in lymph nodes occurs in three distinct phases, Nature, vol.427, issue.6970, pp.154-163, 2004.
DOI : 10.1038/nature02238

K. H. Mills, Regulatory T cells: friend or foe in immunity to infection?, Nature Reviews Immunology, vol.170, issue.11, pp.841-55, 2004.
DOI : 10.1002/1521-4141(200211)32:11<3267::AID-IMMU3267>3.0.CO;2-1

F. Miyagawa and Y. Tanaka, Essential Requirement of Antigen Presentation by Monocyte Lineage Cells for the Activation of Primary Human ???? T Cells by Aminobisphosphonate Antigen, The Journal of Immunology, vol.166, issue.9, pp.5508-5522, 2001.
DOI : 10.4049/jimmunol.166.9.5508

C. T. Morita and E. M. Beckman, Direct presentation of nonpeptide prenyl pyrophosphate antigens to human ???? T cells, Immunity, vol.3, issue.4, pp.495-507, 1995.
DOI : 10.1016/1074-7613(95)90178-7

C. Munz and R. M. Steinman, Dendritic cell maturation by innate lymphocytes: Figure 1., The Journal of Experimental Medicine, vol.62, issue.2, pp.203-210, 2005.
DOI : 10.1126/science.1068440

M. J. Newport and C. M. Huxley, A Mutation in the Interferon-?? ???Receptor Gene and Susceptibility to Mycobacterial Infection, New England Journal of Medicine, vol.335, issue.26, pp.1941-1950, 1996.
DOI : 10.1056/NEJM199612263352602

O. 'brien, R. L. , and M. P. Happ, Stimulation of a major subset of lymphocytes expressing T cell receptor ???? by an antigen derived from mycobacterium tuberculosis, Cell, vol.57, issue.4, pp.667-74, 1989.
DOI : 10.1016/0092-8674(89)90135-9

O. Doherty, U. , and M. Peng, Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature, Immunology, vol.82, issue.3, pp.487-93, 1994.

J. Oliaro and S. Dudal, V??9V??2 T cells use a combination of mechanisms to limit the spread of the pathogenic bacteria Brucella, Journal of Leukocyte Biology, vol.77, issue.5, pp.652-60, 2005.
DOI : 10.1189/jlb.0704433

J. Olweus and A. Bitmansour, Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin, Proceedings of the National Academy of Sciences, vol.94, issue.23, pp.12551-12557, 1997.
DOI : 10.1073/pnas.94.23.12551

J. Pacanowski and S. Kahi, Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection, Blood, vol.98, issue.10, pp.3016-3037, 2001.
DOI : 10.1182/blood.V98.10.3016

K. Pfeffer and B. Schoel, Primary responses of human T cells to mycobacteria: a frequent set of ??/?? T cells are stimulated by protease-resistant ligands, European Journal of Immunology, vol.341, issue.5, pp.1175-1184, 1990.
DOI : 10.1002/eji.1830200534

F. Poccia and C. Agrati, V??9V??2 T cell-mediated non-cytolytic antiviral mechanisms and their potential for cell-based therapy, Immunology Letters, vol.100, issue.1, pp.14-20, 2005.
DOI : 10.1016/j.imlet.2005.06.025

F. Poccia and B. Cipriani, CD94/NKG2 inhibitory receptor complex modulates both anti-viral and anti-tumoral responses of polyclonal phosphoantigen-reactive V gamma 9V delta 2 T lymphocytes, J Immunol, vol.159, issue.12, pp.6009-6026, 1997.

Y. Poquet and P. Constant, A novel nucleotide-containing antigen for human blood ???? T lymphocytes, European Journal of Immunology, vol.25, issue.10, pp.2344-2353, 1996.
DOI : 10.1002/eji.1830261011

URL : https://hal.archives-ouvertes.fr/hal-00177985

T. I. Prigozy and P. A. Sieling, The Mannose Receptor Delivers Lipoglycan Antigens to Endosomes for Presentation to T Cells by CD1b Molecules, Immunity, vol.6, issue.2, pp.187-97, 1997.
DOI : 10.1016/S1074-7613(00)80425-2

S. Raziuddin and N. A. Mir, ???? T lymphocytes and proinflammatory cytokines in bacterial meningitis, Journal of Allergy and Clinical Immunology, vol.93, issue.4, pp.793-801, 1994.
DOI : 10.1016/0091-6749(94)90260-7

B. Rincon-orozco and V. Kunzmann, Activation of V??9V??2 T Cells by NKG2D, The Journal of Immunology, vol.175, issue.4, pp.2144-51, 2005.
DOI : 10.4049/jimmunol.175.4.2144

M. Rohmer and M. Knani, Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate, Biochemical Journal, vol.295, issue.2, pp.517-541, 1993.
DOI : 10.1042/bj2950517

M. G. Rudolph and C. Wingren, Combined pseudo-merohedral twinning, non-crystallographic symmetry and pseudo-translation in a monoclinic crystal form of the ???? T-cell ligand T10, Acta Crystallographica Section D Biological Crystallography, vol.60, issue.4, pp.656-64, 2004.
DOI : 10.1107/S0907444904002239

F. Sallusto and A. Lanzavecchia, Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha, Journal of Experimental Medicine, vol.179, issue.4, pp.1109-1127, 1994.
DOI : 10.1084/jem.179.4.1109

K. Sano and H. Tomioka, Interaction of Antimycobacterial Drugs with the Anti-Mycobacterium avium Complex Effects of Antimicrobial Effectors, Reactive Oxygen Intermediates, Reactive Nitrogen Intermediates, and Free Fatty Acids Produced by Macrophages, Antimicrobial Agents and Chemotherapy, vol.48, issue.6, pp.2132-2141, 2004.
DOI : 10.1128/AAC.48.6.2132-2139.2004

F. Scalise and R. Gerli, Lymphocytes bearing the gamma delta T-cell receptor in acute toxoplasmosis, Immunology, vol.76, issue.4, pp.668-70, 1992.

L. S. Schlesinger, Role of mononuclear phagocytes in M tuberculosis pathogenesis, J Investig Med, vol.44, issue.6, pp.312-335, 1996.

L. S. Schlesinger and M. A. Horwitz, Phagocytosis of Mycobacterium leprae by human monocyte-derived EPHE Banque de Monographies SVT macrophages is mediated by complement receptors CR1 (CD35), CR3 (CD11b/CD18), and CR4 (CD11c/CD18) and IFN-gamma activation inhibits complement receptor function and phagocytosis of this bacterium, J Immunol, vol.147, issue.6, pp.1983-94, 1991.

L. S. Schlesinger and S. R. Hull, Binding of the terminal mannosyl units of lipoarabinomannan from a virulent strain of Mycobacterium tuberculosis to human macrophages, J Immunol, vol.152, issue.8, pp.4070-4079, 1994.

E. Scotet and L. O. Martinez, Tumor Recognition following V??9V??2 T Cell Receptor Interactions with a Surface F1-ATPase-Related Structure and Apolipoprotein A-I, Immunity, vol.22, issue.1, pp.71-80, 2005.
DOI : 10.1016/j.immuni.2004.11.012

L. K. Selin and S. Stewart, Reactivity of gammadelta T Cells Induced by the Tumour Cell Line RPMI 8226: Functional Heterogeneity of Clonal Populations and Role of GroEL Heat Shock Proteins, Scandinavian Journal of Immunology, vol.30, issue.1, pp.107-124, 1992.
DOI : 10.1016/0167-5699(90)90133-T

Y. Shen and D. Zhou, Adaptive Immune Response of Vgamma 2Vdelta 2+ T Cells During Mycobacterial Infections, Science, vol.295, issue.5563, pp.2255-2263, 2002.
DOI : 10.1126/science.1068819

H. Sicard and S. Ingoure, In Vivo Immunomanipulation of V??9V??2 T Cells with a Synthetic Phosphoantigen in a Preclinical Nonhuman Primate Model, The Journal of Immunology, vol.175, issue.8, pp.5471-80, 2005.
DOI : 10.4049/jimmunol.175.8.5471

G. Sireci and E. Espinosa, Differential activation of human ??????? cells by nonpeptide phosphoantigens, European Journal of Immunology, vol.31, issue.5, pp.1628-1663, 2001.
DOI : 10.1002/1521-4141(200105)31:5<1628::AID-IMMU1628>3.0.CO;2-T

S. Stenger and D. A. Hanson, An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin, Science, vol.282, issue.5386, pp.121-126, 1998.
DOI : 10.1126/science.282.5386.121

S. Stenger and R. J. Mazzaccaro, Differential Effects of Cytolytic T Cell Subsets on Intracellular Infection, Science, vol.276, issue.5319, pp.1684-1691, 1997.
DOI : 10.1126/science.276.5319.1684

S. Stoll and J. Delon, Dynamic Imaging of T Cell-Dendritic Cell Interactions in Lymph Nodes, Science, vol.296, issue.5574, pp.1873-1879, 2002.
DOI : 10.1126/science.1071065

Y. Tanaka and C. T. Morita, Natural and synthetic non-peptide antigens recognized by human ???? T cells, Nature, vol.375, issue.6527, pp.155-163, 1995.
DOI : 10.1038/375155a0

G. S. Timmins and S. Master, Requirements for Nitric Oxide Generation from Isoniazid Activation In Vitro and Inhibition of Mycobacterial Respiration In Vivo, Journal of Bacteriology, vol.186, issue.16, pp.5427-5458, 2004.
DOI : 10.1128/JB.186.16.5427-5431.2004

K. Tsukaguchi and K. N. Balaji, CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production, J Immunol, vol.154, issue.4, pp.1786-96, 1995.

S. A. Vaidya and G. Cheng, Toll-like receptors and innate antiviral responses, Current Opinion in Immunology, vol.15, issue.4, pp.402-409, 2003.
DOI : 10.1016/S0952-7915(03)00070-0

H. J. Van-der-vliet and N. Nishi, Potent expansion of human natural killer T cells using ??-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15, Journal of Immunological Methods, vol.247, issue.1-2, pp.61-72, 2001.
DOI : 10.1016/S0022-1759(00)00272-6

I. Vergne and J. Chua, Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis, Proceedings of the National Academy of Sciences, vol.102, issue.11, pp.4033-4041, 2005.
DOI : 10.1073/pnas.0409716102

M. Von-lilienfeld-toal and J. Nattermann, Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p44 and show cytotoxic activity against myeloma cells, Clinical and Experimental Immunology, vol.167, issue.3, pp.528-561, 2006.
DOI : 10.1182/blood-2004-04-1422

F. Winau and S. Weber, Apoptotic Vesicles Crossprime CD8 T Cells and Protect against Tuberculosis, Immunity, vol.24, issue.1, pp.105-122, 2006.
DOI : 10.1016/j.immuni.2005.12.001